Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs886039902
rs886039902
ANKRD11
C 0.700 CausalMutation CLINVAR

dbSNP: rs17580
rs17580
SERPINA1
0.010 GeneticVariation BEFREE The associations of SERPINA1 Z (rs28929474) and S (rs17580) alleles with age at CFLD onset and the development of CFLD-related complications (severe liver disease with cirrhosis, portal hypertension, esophageal varices) were analyzed. 30739910

2019
dbSNP: rs28929474
rs28929474
SERPINA1
0.010 GeneticVariation BEFREE The associations of SERPINA1 Z (rs28929474) and S (rs17580) alleles with age at CFLD onset and the development of CFLD-related complications (severe liver disease with cirrhosis, portal hypertension, esophageal varices) were analyzed. 30739910

2019
dbSNP: rs1275561861
rs1275561861
HLA-A
0.010 GeneticVariation BEFREE A 57-year-old white woman had serum ferritin 793 ng/mL, HFE C282Y homozygosity, elevated serum angiotensin-converting enzyme (ACE) levels, 3+ hepatocyte iron, cirrhosis, hepatic granulomas, and portal hypertension. 19440063

2009
dbSNP: rs1290778035
rs1290778035
ACE
0.010 GeneticVariation BEFREE A 57-year-old white woman had serum ferritin 793 ng/mL, HFE C282Y homozygosity, elevated serum angiotensin-converting enzyme (ACE) levels, 3+ hepatocyte iron, cirrhosis, hepatic granulomas, and portal hypertension. 19440063

2009
dbSNP: rs1800562
rs1800562
HFE ; LOC108783645
0.010 GeneticVariation BEFREE A 57-year-old white woman had serum ferritin 793 ng/mL, HFE C282Y homozygosity, elevated serum angiotensin-converting enzyme (ACE) levels, 3+ hepatocyte iron, cirrhosis, hepatic granulomas, and portal hypertension. 19440063

2009
dbSNP: rs1267969615
rs1267969615
ACE
0.010 GeneticVariation BEFREE We evaluated the relationship between genetic polymorphisms of the renin-angiotensin system (A1166C angiotensin II type 1 receptor (AT1R), angiotensinogen T174M and M235T, and angiotensin-converting enzyme I/D) and the effects of losartan on portal and systemic hemodynamic in patients with cirrhosis and portal hypertension. 15743363

2005
dbSNP: rs4762
rs4762
AGT
0.010 GeneticVariation BEFREE We evaluated the relationship between genetic polymorphisms of the renin-angiotensin system (A1166C angiotensin II type 1 receptor (AT1R), angiotensinogen T174M and M235T, and angiotensin-converting enzyme I/D) and the effects of losartan on portal and systemic hemodynamic in patients with cirrhosis and portal hypertension. 15743363

2005
dbSNP: rs699
rs699
AGT
0.010 GeneticVariation BEFREE We evaluated the relationship between genetic polymorphisms of the renin-angiotensin system (A1166C angiotensin II type 1 receptor (AT1R), angiotensinogen T174M and M235T, and angiotensin-converting enzyme I/D) and the effects of losartan on portal and systemic hemodynamic in patients with cirrhosis and portal hypertension. 15743363

2005