|
rs121907892
|
|
|
0.030 |
GeneticVariation |
BEFREE |
She had compound heterozygous mutations in this gene (W258X and IVS2+1G>A), nevertheless, she showed no clinical manifestations such as urolithiasis and exercise-induced acute renal failure.
|
16724660 |
2006 |
|
rs782818582
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Novel compound heterozygote mutations (H234Q/R1206X) of the ADAMTS13 gene in an adult patient with Upshaw-Schulman syndrome showing predominant episodes of repeated acute renal failure.
|
16449289 |
2006 |
|
rs121907892
|
|
|
0.030 |
GeneticVariation |
BEFREE |
The patient had compound heterozygous mutations in the hURAT1 gene (R90H and W258X), but showed no clinical manifestations such as urolithiasis or exercise-induced acute renal failure.
|
17362586 |
2007 |
|
rs121907896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The patient had compound heterozygous mutations in the hURAT1 gene (R90H and W258X), but showed no clinical manifestations such as urolithiasis or exercise-induced acute renal failure.
|
17362586 |
2007 |
|
rs121907892
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We here described a 25-yr-old man showing idiopathic renal hypouricemia with G774A mutation in SCL22A12 who presented exercise-induced acute renal failure.
|
21935282 |
2011 |
|
rs1451506414
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We here described a 25-yr-old man showing idiopathic renal hypouricemia with G774A mutation in SCL22A12 who presented exercise-induced acute renal failure.
|
21935282 |
2011 |
|
rs12457893
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these were in the BCL2 gene and both were associated with a decreased risk of acute kidney injury (rs8094315: odds ratio 0.61, p = .0002; rs12457893: odds ratio 0.67, p = .0002, both for combined data).
|
22710204 |
2012 |
|
rs1444669684
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Both tumors develop in mice upon conditional deletion in melanocytes of Ink4a/Arf tumor suppressor genes with concomitant expression of oncogene H-Ras(G12V) and a known tumor antigen.
|
23173060 |
2012 |
|
rs561633150
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that homozygous and/or compound heterozygous loss-of-function mutations p.G216R and p.N333S cause renal hypouricaemia via loss of uric acid absorption and do lead to acute kidney injury.
|
22527535 |
2012 |
|
rs753482595
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings suggest that homozygous and/or compound heterozygous loss-of-function mutations p.G216R and p.N333S cause renal hypouricaemia via loss of uric acid absorption and do lead to acute kidney injury.
|
22527535 |
2012 |
|
rs8094315
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Two of these were in the BCL2 gene and both were associated with a decreased risk of acute kidney injury (rs8094315: odds ratio 0.61, p = .0002; rs12457893: odds ratio 0.67, p = .0002, both for combined data).
|
22710204 |
2012 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
COMT-Val158Met-polymorphism is not a risk factor for acute kidney injury after cardiac surgery.
|
24167357 |
2013 |
|
rs1800629
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The TNFA rs1800629 gene polymorphism is associated with markers of kidney disease severity and distant organ dysfunction among patients with AKI.
|
23796916 |
2013 |
|
rs775020499
|
|
|
0.010 |
GeneticVariation |
BEFREE |
COMT-Val158Met-polymorphism is not a risk factor for acute kidney injury after cardiac surgery.
|
24167357 |
2013 |
|
rs4680
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Pilot study of association of catechol-O-methyl transferase rs4680 genotypes with acute kidney injury and tubular stress after open heart surgery.
|
25525983 |
2014 |
|
rs1370328347
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians.
|
24059882 |
2014 |
|
rs1800470
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the genetic polymorphisms of rs1800470 (codon 10 T/C), rs1800471 (codon 25 C/G) from the TGF-β, and rs2430561 (+874 T/A) from IFN-γ may be a risk factor for ICU patients to the development of AKI and/or death.
|
25147823 |
2014 |
|
rs1800471
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the genetic polymorphisms of rs1800470 (codon 10 T/C), rs1800471 (codon 25 C/G) from the TGF-β, and rs2430561 (+874 T/A) from IFN-γ may be a risk factor for ICU patients to the development of AKI and/or death.
|
25147823 |
2014 |
|
rs2430561
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To investigate whether the genetic polymorphisms of rs1800470 (codon 10 T/C), rs1800471 (codon 25 C/G) from the TGF-β, and rs2430561 (+874 T/A) from IFN-γ may be a risk factor for ICU patients to the development of AKI and/or death.
|
25147823 |
2014 |
|
rs767816037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Apolipoprotein E genotype, TNF-α 308G/A and risk for cardiac surgery associated-acute kidney injury in Caucasians.
|
24059882 |
2014 |
|
rs1050851
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In Caucasian patients, we identified associations between two SNPs and the incidence of AKI (stage 1 and above): rs1050851 and rs2233417; both are found within the gene for nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA).
|
26477820 |
2015 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients with the TT-homozygous genotype of eNOS G894T had more severe PUUV-induced AKI than the other genotypes.
|
26561052 |
2015 |
|
rs2233417
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In Caucasian patients, we identified associations between two SNPs and the incidence of AKI (stage 1 and above): rs1050851 and rs2233417; both are found within the gene for nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (NFKBIA).
|
26477820 |
2015 |
|
rs2276415
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A χ(2)-test and multivariable logistic regression analysis with adjustments for age, sex, baseline serum creatinine, and underlying comorbid disease covariates showed a significant association between rs2276415 and the prevalence of any event of acute kidney injury and chronic kidney disease (CKD) in diabetic patients but not in patients without diabetes.
|
26719361 |
2016 |
|
rs10854554
|
|
|
0.010 |
GeneticVariation |
BEFREE |
These include rs62341639 (metaanalysis P = 2.48 × 10<sup>-7</sup>; odds ratio [OR], 0.64; 95% confidence interval [CI], 0.55-0.76) and rs62341657 (P = 3.26 × 10<sup>-7</sup>; OR, 0.65; 95% CI, 0.55-0.76) on chromosome 4 near APOL1-regulator IRF2, and rs9617814 (metaanalysis P = 3.81 × 10<sup>-6</sup>; OR, 0.70; 95% CI, 0.60-0.81) and rs10854554 (P = 6.53 × 10<sup>-7</sup>; OR, 0.67; 95% CI, 0.57-0.79) on chromosome 22 near acute kidney injury-related gene TBX1.
|
27576016 |
2017 |