Haplotype analysis indicated a combination of allele A of rs57095329 and allele G of rs2910164 could represent a risk haplotype and an allele combination of G of rs57095329 and G of rs2910164 could represent a protective haplotype for ALL.
We found that the rs2910164 G>C variant of hsa-miR-146a significantly increased the risk of ALL (CC vs. GG, OR = 4.24, 95% CI = 1.52-11.87, P = 0.006; GC vs. GG, OR = 3.55, 95% CI = 1.41-8.93, P = 0.007; C vs. T, OR = 1.73, 95% CI = 1.13-2.67, P = 0.012).