Gene: RUNX1 ×
Source: BEFREE ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs2249650
rs2249650
RUNX1
0.010 GeneticVariation BEFREE To sum up, rs2268276 and especially rs2249650 may be qualified as new acute myeloid leukemia susceptibility-associated SNPs. 26374622

2016
dbSNP: rs2268276
rs2268276
RUNX1
0.010 GeneticVariation BEFREE To sum up, rs2268276 and especially rs2249650 may be qualified as new acute myeloid leukemia susceptibility-associated SNPs. 26374622

2016
dbSNP: rs757412228
rs757412228
RUNX1
0.010 GeneticVariation BEFREE We identified TET2 and PTPN11 mutations in both mouse and human AML and then demonstrated the ability of Tet2 loss and PTPN11 D61Y to initiate leukemogenesis in concert with expression of AML1-ETO in vivo. 26666262

2016
dbSNP: rs1482518887
rs1482518887
RUNX1
0.010 GeneticVariation BEFREE KRAS (G12D) cooperates with AML1/ETO to initiate a mouse model mimicking human acute myeloid leukemia. 24480914

2014
dbSNP: rs74315450
rs74315450
RUNX1
0.010 GeneticVariation BEFREE RUNX1, which regulates a gene for hematopoiesis, is frequently mutated in AML and, in this study, one out of three patients showed the mutation R174Q in RUNX1. 20694842

2010