|
rs721917
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Regarding rs721917, the T allele may increase the risk of chronic obstructive pulmonary disease</span> in the Asian population.
|
31116231 |
2019 |
|
rs721917
|
|
|
0.740 |
GeneticVariation |
BEFREE |
Significant association of risk was also observed for "T" allele or "TT" genotype of rs721917 from SFTPD with COPD and AECOPD.
|
31057601 |
2019 |
|
rs721917
|
|
G |
0.740 |
GeneticVariation |
GWASCAT |
Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations.
|
30804561 |
2019 |
|
rs721917
|
|
G |
0.740 |
GeneticVariation |
GWASCAT |
Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis.
|
28166215 |
2017 |
|
rs721917
|
|
|
0.740 |
GeneticVariation |
BEFREE |
We report for the first time that rs3088308 is an important factor influencing systemic SP-D levels and confirm the previous association of rs721917 to the risk of COPD and serum SP-D levels.
|
22846212 |
2012 |
|
rs721917
|
|
|
0.740 |
GeneticVariation |
BEFREE |
In the NETT-NAS case-control analysis, four SFTPD SNPs were associated with susceptibility to COPD: rs2245121 (P = 0.01), rs911887 (P = 0.006), rs6413520 (P = 0.004), and rs721917 (P = 0.006).
|
20448057 |
2011 |
|
rs7078012
|
|
T |
0.710 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
|
23144326 |
2012 |
|
rs7078012
|
|
|
0.710 |
GeneticVariation |
BEFREE |
An intronic SNP in SFTPD, rs7078012, was associated with COPD in the ECLIPSE Study and the Bergen Cohort.
|
20448057 |
2011 |
|
rs3923564
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
|
23144326 |
2012 |
|
rs2243639
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that rs2243639 is not related to the risk of chronic obstructive pulmonary disease in the Asian population but is related to this risk in the Caucasian population.
|
31116231 |
2019 |
|
rs2243639
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Smokers who were carriers of the polymorphic SFTPD rs2243639 A allele (AG and AA genotypes) have a 2.708 times risk of developing COPD when compared with wild-type GG genotype carriers [odds ratio (OR) 2.708 (95 % CI 1.041-7.047)].
|
24504887 |
2014 |
|
rs2243639
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Two SNPs in TGFB1 (C to T substitution at nucleotide -509 and substitution of leucine 10 with proline (Leu10Pro)), Leu50Val in SFTPA1 and Ala160Thr in SFTPD showed evidence suggestive of association with FEV(1)/IVC in subjects with GOLD stage >or=2 COPD.
|
19797132 |
2010 |
|
rs3088308
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We report for the first time that rs3088308 is an important factor influencing systemic SP-D levels and confirm the previous association of rs721917 to the risk of COPD and serum SP-D levels.
|
22846212 |
2012 |
|
rs2245121
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the NETT-NAS case-control analysis, four SFTPD SNPs were associated with susceptibility to COPD: rs2245121 (P = 0.01), rs911887 (P = 0.006), rs6413520 (P = 0.004), and rs721917 (P = 0.006).
|
20448057 |
2011 |
|
rs6413520
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the NETT-NAS case-control analysis, four SFTPD SNPs were associated with susceptibility to COPD: rs2245121 (P = 0.01), rs911887 (P = 0.006), rs6413520 (P = 0.004), and rs721917 (P = 0.006).
|
20448057 |
2011 |
|
rs911887
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In the NETT-NAS case-control analysis, four SFTPD SNPs were associated with susceptibility to COPD: rs2245121 (P = 0.01), rs911887 (P = 0.006), rs6413520 (P = 0.004), and rs721917 (P = 0.006).
|
20448057 |
2011 |