Source: GWASDB ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs7574865
rs7574865
STAT4
T 0.900 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463

2014
dbSNP: rs2230926
rs2230926
TNFAIP3
G 0.900 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs7574865
rs7574865
STAT4
T 0.900 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs7574865
rs7574865
STAT4
T 0.900 GeneticVariation GWASDB Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. 23053960

2012
dbSNP: rs7574865
rs7574865
STAT4
T 0.900 GeneticVariation GWASDB For example, rs7574865 in STAT4 had an OR for anti-dsDNA + SLE of 1.77 (95% CI 1.57-1.99, p = 2.0E-20) compared to an OR for anti-dsDNA - SLE of 1.26 (95% CI 1.12-1.41, p = 2.4E-04), with p(heterogeneity)<0.0005. 21408207

2011
dbSNP: rs1143679
rs1143679
ITGAM
0.900 GeneticVariation GWASDB ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai. 19286673

2009
dbSNP: rs2230926
rs2230926
TNFAIP3
C 0.900 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193

2009
dbSNP: rs7574865
rs7574865
STAT4
A 0.900 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193

2009
dbSNP: rs7574865
rs7574865
STAT4
0.900 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446

2008
dbSNP: rs7574865
rs7574865
STAT4
T 0.900 GeneticVariation GWASDB Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. 18204098

2008
dbSNP: rs13277113
rs13277113
BLK
0.890 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs13277113
rs13277113
BLK
A 0.890 GeneticVariation GWASDB Genome-wide pathway analysis of genome-wide association studies on systemic lupus erythematosus and rheumatoid arthritis. 23053960

2012
dbSNP: rs13277113
rs13277113
BLK
0.890 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193

2009
dbSNP: rs13277113
rs13277113
BLK
A 0.890 GeneticVariation GWASDB Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. 18204098

2008
dbSNP: rs2205960
rs2205960
TNFSF4
T 0.880 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs2205960
rs2205960
TNFSF4
A 0.880 GeneticVariation GWASDB Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. 19838193

2009
dbSNP: rs10516487
rs10516487
BANK1
G 0.880 GeneticVariation GWASDB In a genome-wide scan using 85,042 SNPs, we identified an association between SLE and a nonsynonymous substitution (rs10516487, R61H) in the B-cell scaffold protein with ankyrin repeats gene, BANK1. 18204447

2008
dbSNP: rs2736340
rs2736340 		0.870 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs2736340
rs2736340 		T 0.870 GeneticVariation GWASDB Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. 21408207

2011
dbSNP: rs17266594
rs17266594
BANK1
0.850 GeneticVariation GWASDB Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. 18204447

2008
dbSNP: rs5029939
rs5029939
TNFAIP3
0.850 GeneticVariation GWASDB We carried out a genome-wide association scan and replication study and found an association between SLE and a variant in TNFAIP3 (rs5029939, meta-analysis P = 2.89 x 10(-12), OR = 2.29). 19165918

2008
dbSNP: rs9271366
rs9271366 		0.840 GeneticVariation GWASDB Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians. 23273568

2013
dbSNP: rs2431697
rs2431697 		0.840 GeneticVariation GWASDB Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. 18204446

2008
dbSNP: rs10488631
rs10488631
TNPO3
C 0.830 GeneticVariation GWASDB GWAS identifies novel SLE susceptibility genes and explains the association of the HLA region. 24871463

2014
dbSNP: rs10488631
rs10488631
TNPO3
C 0.830 GeneticVariation GWASDB Differential genetic associations for systemic lupus erythematosus based on anti-dsDNA autoantibody production. 21408207

2011