|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Conclusion CD11b rs1143679 appears to be associated with risk for SLE in the Han Chinese population, and may play an important role in the development of lupus nephritis.
|
29207897 |
2018 |
|
rs7708392
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggested that TNIP1 SNP (rs7708392) might be associated with the LN</span> in Egyptian SLE patients.
|
29589214 |
2018 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The objective of this study was to identify the association between genotypes of miR-146a rs2910164 and expression of TRAF6 as well as the risk of lupus nephritis (LN).
|
29754557 |
2017 |
|
rs2910164
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report documenting that the <i>miR-146a</i> rs2910164G/C and <i>miR-499</i> rs3746444 polymorphisms are associated with SLE susceptibility but not with LN.
|
29190882 |
2017 |
|
rs352140
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A significant genotypic and allelic association was revealed between TLR-9-rs352140 and both SLE and LN (P < 0·05).
|
28763101 |
2017 |
|
rs1143679
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our meta-analyses confirm that the ITGAM rs1143679 polymorphism is associated with SLE susceptibility in different ethnic groups and demonstrate that the polymorphism is associated with LN in European.
|
25315704 |
2015 |
|
rs7708392
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Comparing cases of systemic lupus erythematosus with nephritis and cases of systemic lupus erythematosus without nephritis revealed strong associations with lupus nephritis at rs7708392 in European Americans and rs4958881 in African Americans.
|
23970121 |
2013 |
|
rs352140
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Both rs352139 (p=0.040, OR: 0.713, 95%CI: 0.516-0.985) and rs352140 (p=0.048, OR: 0.723, 95%CI: 0.525-0.997) were associated with LN in dominant model.
|
20497632 |
2010 |
|
rs11203368
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Carriage of minor alleles of five other SNPs (rs11203366, rs11203367, rs874881, rs2240340, and rs11203368) was associated with increased occurrence of LN and hypertension.
|
30269634 |
2019 |
|
rs117026326
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Patients carrying genotype TT of rs117026326 had lower 24-hour urinary total protein (24 hours UTP, g/24 hours), 24-hour urinary protein level (g/L·24 hours), lower frequency of the proteinuria and lupus nephritis (LN).
|
31374066 |
2019 |
|
rs1635564
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Notably, gene dose effects of the rs1635564 variant allele were observed for SLE (p = 0.005) and LN (p = 0.01).
|
30269634 |
2019 |
|
rs6478109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes distribution of rs6478109, rs7848647 were strongly related to lupus nephritis within SLE (p = 0.004, p = 0.011), respectively.
|
31081141 |
2019 |
|
rs7848647
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genotypes distribution of rs6478109, rs7848647 were strongly related to lupus nephritis within SLE (p = 0.004, p = 0.011), respectively.
|
31081141 |
2019 |
|
rs8193037
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The aim of this study was to investigate whether the IL-17A -737 T/C (rs8193036), -444A/G (rs3819024), -197G/A (rs2275913), and -121G/A (rs8193037) SNPs conferred susceptibility to SLE (or lupus nephritis) or to RA in a Mexican population.
|
30398030 |
2019 |
|
rs1799964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Here, we aimed to examine whether the TNF -238G/A, -308G/A, -376G/A (rs1800750), and -1031T/C (rs1799964) polymorphisms confer SLE or lupus nephritis (LN) susceptibility in a Mexican population.
|
29611038 |
2018 |
|
rs3824662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GATA3 rs3824662 is not associated with susceptibility to SLE either in adult or in pediatric patients; however, in pSLE patients, the heterozygous AC genotype could be considered a risk factor for LN.
|
30301440 |
2018 |
|
rs8091180
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The SNP rs8091180 in NFATC1 was associated with LN (OR 1.43, p = 3.3E-04) in the candidate SNP meta-analysis with the highest OR among African-Americans (OR 2.17, p = 0.0035).
|
29953444 |
2018 |
|
rs1061170
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There was a significantly higher ratio of CC/CT genotypes of rs1061170 in lupus nephritis patients with class III than in the other two classes (class III vs. class IV vs. class V: 21.0% vs. 9.7% vs. 9.4%; P = .044).
|
28403670 |
2017 |
|
rs114580964
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We discovered five independent risk variants for LN within the MHC region, including <i>HLA-DRβ1</i> amino acid 11 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DQβ1</i> amino acid 45 (<i>P</i><0.001; odds ratio, 0.58; 95% confidence interval, 0.52 to 0.65), <i>HLA-A</i> amino acid 156 (<i>P</i><sub>omnibus</sub><0.001), <i>HLA-DPβ1</i> amino acid 76 (<i>P</i><sub>omnibus</sub><0.001), and a missense variant in <i>PRRC2A</i> (rs114580964; <i>P</i><0.001; odds ratio, 0.38; 95% confidence interval, 0.30 to 0.49) at genome-wide significance.
|
28754791 |
2017 |
|
rs1456896
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that the rs1456896 A allele is associated with protective susceptibility to LN.
|
27684961 |
2017 |
|
rs3746444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This is the first report documenting that the <i>miR-146a</i> rs2910164G/C and <i>miR-499</i> rs3746444 polymorphisms are associated with SLE susceptibility but not with LN.
|
29190882 |
2017 |
|
rs5744168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No allelic nor genotype association was found with TLR-5-rs5744168 in SLE. but the T allele and the TT genotype were raised significantly in the LN group (P < 0·05).
|
28763101 |
2017 |
|
rs6677604
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs6677604-GG genotype was observed to be associated with the absence of anti-ds DNA antibody ( P = .021), and the rs800292-TT genotype was associated with a higher level of circulating C3 ( P = 0.20) in lupus nephritis.
|
28403670 |
2017 |
|
rs800292
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs6677604-GG genotype was observed to be associated with the absence of anti-ds DNA antibody ( P = .021), and the rs800292-TT genotype was associated with a higher level of circulating C3 ( P = 0.20) in lupus nephritis.
|
28403670 |
2017 |
|
rs2275913
|
|
|
0.010 |
GeneticVariation |
BEFREE |
IL-17A rs2275913, IL-17F rs763780 and rs2397084 are not related to the LN development, SLE disease activity or overall survival.
|
26515887 |
2016 |