rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
However, we did not find any association of polymorphism of XRCC1 Arg399Gln (OR = 1.56; 95% CI: 0.32-7.82) and XPD Lys751Gln (OR = 0.46; CI: 0.10-2.19) with GC risk in the study population.
|
30225185 |
2018 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Furthermore, the ERCC2 Asp312Asn polymorphism is associated with bladder, esophageal, and gastric cancers, but not with breast, head and neck, lung, prostate, and skin cancers, and non-Hodgkin lymphoma.
|
28489582 |
2017 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
However, we found no association between ERCC1 rs11615, ERCC2 rs13181, and ERCC2 rs1799793 and overall survival of gastric cancer.
|
27173253 |
2016 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
However, we found no association between ERCC1 rs11615, ERCC2 rs13181, and ERCC2 rs1799793 and overall survival of gastric cancer.
|
27173253 |
2016 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In conclusion, our finding suggests that ERCC1 rs3212986 and ERCC2 rs13181 gene polymorphism could influence the response to chemotherapy and clinical outcome of gastric cancer.
|
26191265 |
2015 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer.
|
26823845 |
2015 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We investigated three genotypes of XPD, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with gastric cancer susceptibility in a Taiwanese population.
|
26254397 |
2015 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We investigated three genotypes of XPD, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with gastric cancer susceptibility in a Taiwanese population.
|
26254397 |
2015 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer.
|
26782397 |
2015 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
By the Cox analysis, the CC genotype of ERCC1 rs11615, AA genotype of ERCC2 rs1799793, and CC genotype of NBN rs1805794 were significantly associated with a longer overall survival (OS) of gastric cancer.
|
25542228 |
2015 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
In conclusion, ERCC1 rs11615, rs2298881 and ERCC2 rs1799793 polymorphism play an important role in the treatment outcome of gastric cancer.
|
26097599 |
2015 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer.
|
26823845 |
2015 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis aimed to obtain a comprehensive and reliable assessment of the relationships between XRCC1 Arg399Gln and XPD Lys751Gln polymorphisms and the clinical outcomes of gastric cancer (GC) patients treated with oxaliplatin-based chemotherapy.
|
24590266 |
2014 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We conclude that ERCC2 rs13181 polymorphism could play different roles in the overall survival of gastric cancer.
|
23680703 |
2013 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
A statistically significant finding could be seen in noncardia-type gastric cancer for XPD Lys751Gln polymorphism.
|
23028453 |
2012 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
We aimed to explore the effect of XPD Lys751Gln and Asp312Asn polymorphisms on the susceptibility to gastric cancer among different ethnicities through a systematic review and meta-analysis.
|
23028453 |
2012 |
rs13181
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis concluded that both ERCC2 Lys751Gln and Asp312Asn polymorphisms might contribute to increased risk of GC among Asians.
|
20981556 |
2011 |
rs1799793
|
|
|
0.090 |
GeneticVariation |
BEFREE |
This meta-analysis concluded that both ERCC2 Lys751Gln and Asp312Asn polymorphisms might contribute to increased risk of GC among Asians.
|
20981556 |
2011 |
rs759412116
|
|
|
0.030 |
GeneticVariation |
BEFREE |
However, we did not find any association of polymorphism of XRCC1 Arg399Gln (OR = 1.56; 95% CI: 0.32-7.82) and XPD Lys751Gln (OR = 0.46; CI: 0.10-2.19) with GC risk in the study population.
|
30225185 |
2018 |
rs759412116
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This meta-analysis aimed to obtain a comprehensive and reliable assessment of the relationships between XRCC1 Arg399Gln and XPD Lys751Gln polymorphisms and the clinical outcomes of gastric cancer (GC) patients treated with oxaliplatin-based chemotherapy.
|
24590266 |
2014 |
rs759412116
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models.
|
20817763 |
2010 |
rs238406
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer.
|
26782397 |
2015 |
rs3810366
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated three genotypes of XPD, at promoter -114 (rs3810366), and codon 312 (rs1799793), 751 (rs13181), and their associated with gastric cancer susceptibility in a Taiwanese population.
|
26254397 |
2015 |
rs1226085679
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphic variants of base excision repair (APE1-D148E, XRCC1-R194W, XRCC1-R399Q and OGG1-S326C), nucleotide excision repair (XPC-PAT, XPA-23G>A, ERCC1-19007T>C and XPD-L751Q), recombination (XRCC3-T241M) and alkylation damage reversal (MGMT-L84F) were tested for their potential role in the development of GC by using logistic regression models.
|
20817763 |
2010 |