|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Our meta-analysis indicated that the <i>ERCC1</i> rs3212986 A/C polymorphism was not associated with response to chemotherapy or overall survival time in GC.
|
29302191 |
2018 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We conducted a prospective study to investigate whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer.
|
27173253 |
2016 |
|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We found that the AA genotype of rs3212986 was correlated with higher risk of death from gastri</span>c cancer according to the Cox proportional hazards model, and the adjusted HR (95%CI) was 1.60 (0.81-3.16).
|
27173253 |
2016 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer.
|
26823845 |
2015 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
By the Cox analysis, the CC genotype of ERCC1 rs11615, AA genotype of ERCC2 rs1799793, and CC genotype of NBN rs1805794 were significantly associated with a longer overall survival (OS) of gastric cancer.
|
25542228 |
2015 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We found that individuals carrying TT genotype of ERCC1 rs11615 and CC genotype of ERCC1 rs2298881 were associated with better response to chemotherapy and longer survival time of gastric cancer.
|
26097599 |
2015 |
|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We performed a study to investigate the role of ERCC1 (rs11615, rs2298881, and rs3212986) and ERCC2 (rs13181, rs238406, and rs1799793) polymorphisms in the prognosis of gastric cancer.
|
26782397 |
2015 |
|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We conducted a prospective study to analyze whether ERCC1 rs11615 and rs3212986 and ERCC2 rs13181 and rs1799793 gene polymorphisms could serve as potential biomarkers for the prognosis of gastric cancer.
|
26823845 |
2015 |
|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, the results of the present retrospective study indicate that there is a significant difference in biological behavior between ERCC1 rs3212986 gene polymorphism and treatment outcome of gastric cancer.
|
26722542 |
2015 |
|
rs3212986
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In conclusion, our finding suggests that ERCC1 rs3212986 and ERCC2 rs13181 gene polymorphism could influence the response to chemotherapy and clinical outcome of gastric cancer.
|
26191265 |
2015 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Moreover, individuals carrying ERCC1 rs11615</span> T allele and rs2298881 C allele could decrease a 0.62-fold risk of death from gastric cancer.
|
24318989 |
2014 |
|
rs11615
|
|
|
0.060 |
GeneticVariation |
BEFREE |
In the Cox propor-tional hazards model, patients carrying the ERCC1 rs11615 AA gen-otype and the XPF rs2276465 GG genotype showed only a 0.22- and 0.30-fold increased risk of death from gastric cancer.
|
25222248 |
2014 |
|
rs2298881
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We found that individuals carrying TT genotype of ERCC1 rs11615 and CC genotype of ERCC1 rs2298881 were associated with better response to chemotherapy and longer survival time of gastric cancer.
|
26097599 |
2015 |
|
rs2298881
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Similarly, we found a significant decreased risk of death from</span> gast</span>ric cancer among patients carrying ERCC1 rs2298881 CC genotype and C allele when compared with CC genotype, and HRs (95% confidence interval (CI)) of OS were 0.50 (0.24-0.98) and 0.62 (0.40-0.96), respectively.
|
24318989 |
2014 |