rs2395182
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
|
20598377 |
2010 |
rs3129871
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.
|
23472185 |
2013 |
rs3129871
|
|
|
0.800 |
GeneticVariation |
GWASDB |
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
|
20598377 |
2010 |
rs3129871
|
|
|
0.800 |
GeneticVariation |
GWASCAT |
Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.
|
23472185 |
2013 |
rs3129872
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs3129877
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs3129882
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Evidence for VAV2 and ZNF433 as susceptibility genes for multiple sclerosis.
|
20598377 |
2010 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
DNA was extracted from blood in order to analyse EBV and HHV-6 viral load by quantitative real-time polymerase chain reaction and to genotype MS-related single nucleotide polymorphisms (rs3135388, rs2248359 and rs12368653) when possible.
|
29996002 |
2018 |
rs3135388
|
|
A |
0.890 |
GeneticVariation |
GWASCAT |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
We observed a trend for association of rs3135388 (HLA-DRB1*1501, p < 0.01), rs7090530 (IL2RA, p < 0.026) and rs1841770 (ZIC1, p < 0.017) with a younger age at MS onset and of rs12044852 (CD58, p < 0.035) with shorter time to reach EDSS6.
|
22411505 |
2012 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
We genotyped a cohort of 1033 MS patients and 644 healthy controls with a consistent genetic background for the 57 non-MHC variants reported to be associated with MS by the first large GWAS as well as the HLA DRB1*1501 tagging SNP rs3135388.
|
26011527 |
2015 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
In quantitative terms, the MS-risk AA genotype carriers of rs3135388 were associated with 15.7-, 5.2- and 8.3-fold higher expression of DQB1, DRB5 and DRB1, respectively, than the non-risk GG carriers.
|
22253788 |
2012 |
rs3135388
|
|
A |
0.890 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Our results indicate that the distribution of the rs3135388 gene polymorphism is a risk factor for MS susceptibility in the Czech female population.
|
23186557 |
2013 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
We analyzed the allelic and genotype frequency of VDR rs2228570, rs731236, and HLADRB1*1501 (rs3135388) in 303 patients with MS and 310 healthy controls, using TaqMan Assays.
|
23840333 |
2013 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Presence of the rs3135388 polymorphism tagging the major MS risk allele HLA-DRB1*15:01 allele was determined as well.
|
28130760 |
2017 |
rs3135388
|
|
A |
0.890 |
GeneticVariation |
GWASDB |
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
|
19525953 |
2009 |
rs3135388
|
|
A |
0.890 |
GeneticVariation |
GWASCAT |
Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
|
19525953 |
2009 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
Our findings show for the first time that the rs3135388</span> polymorphism is a strong risk factor for MS in the Slovak population.
|
25958306 |
2015 |
rs3135388
|
|
|
0.890 |
GeneticVariation |
BEFREE |
The tag SNP for HLA-DRB1*1501, rs3135388, is significantly associated with multiple sclerosis susceptibility: cost-effective high-throughput detection by real-time PCR.
|
19433080 |
2009 |
rs3135388
|
|
A |
0.890 |
GeneticVariation |
GWASCAT |
Genetic variants are major determinants of CSF antibody levels in multiple sclerosis.
|
25616667 |
2015 |
rs3135391
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The most significantly MS-associated SNP in the discovery dataset was rs3135391, a Class II SNP known to tag the HLA-DRB1*15:01 allele, the primary MS susceptibility allele in the MHC (O.R.= 3.04, p < 1 x 10(-78)).
|
20593013 |
2010 |
rs3135392
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs3177928
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |
rs7194
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Risk alleles for multiple sclerosis identified by a genomewide study.
|
17660530 |
2007 |