Gene: RET ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs79658334
rs79658334
RET
A 0.700 GeneticVariation CLINVAR

dbSNP: rs79890926
rs79890926
RET
G 0.700 CausalMutation CLINVAR "Familial associations in medullary thyroid carcinoma with Hirschsprung disease: the role of the RET-C620 ""Janus"" genetic variation." 20152359

2010
dbSNP: rs79658334
rs79658334
RET
T 0.700 CausalMutation CLINVAR A GTG to ATG novel point mutation at codon 804 in exon 14 of the RET proto-oncogene in two families affected by familial medullary thyroid carcinoma. 9452077

1998
dbSNP: rs76262710
rs76262710
RET
A 0.700 CausalMutation CLINVAR A Korean family of familial medullary thyroid cancer with Cys618Ser RET germline mutation. 20119574

2010
dbSNP: rs75030001
rs75030001
RET
T 0.700 CausalMutation CLINVAR A new hot spot for mutations in the ret protooncogene causing familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2A. 9506724

1998
dbSNP: rs146646971
rs146646971
RET
C 0.700 CausalMutation CLINVAR A newly identified missense mutation in RET codon 666 is associated with the development of medullary thyroid carcinoma. 25319874

2014
dbSNP: rs79658334
rs79658334
RET
T 0.700 CausalMutation CLINVAR A NOVEL DOUBLE MUTATION VAL648ILE AND VAL804LEU OF RET PROTO-ONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2. 26247112

2015
dbSNP: rs79658334
rs79658334
RET
T 0.700 CausalMutation CLINVAR A novel point mutation in the intracellular domain of the ret protooncogene in a family with medullary thyroid carcinoma. 9398735

1997
dbSNP: rs377767406
rs377767406
RET
T 0.700 CausalMutation CLINVAR A patient with MEN 2 and multiple mutations of RET in the germline. 11149622

2000
dbSNP: rs377767406
rs377767406
RET
T 0.700 CausalMutation CLINVAR A rare extracellular D631Y germline mutation of the RET proto-oncogene in two Korean families with multiple endocrine neoplasia 2A. 16839264

2006
dbSNP: rs143795581
rs143795581
RET
G 0.700 CausalMutation CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381

2015
dbSNP: rs146646971
rs146646971
RET
T 0.700 CausalMutation CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381

2015
dbSNP: rs79658334
rs79658334
RET
T 0.700 CausalMutation CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381

2015
dbSNP: rs75076352
rs75076352
RET
C 0.700 CausalMutation CLINVAR Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. 7824936

1995
dbSNP: rs75030001
rs75030001
RET
T 0.700 CausalMutation CLINVAR Bilateral adrenal pheochromocytoma with a germline L790F mutation in the RET oncogene. 22403753

2012
dbSNP: rs79658334
rs79658334
RET
T 0.700 CausalMutation CLINVAR Biological and biochemical properties of Ret with kinase domain mutations identified in multiple endocrine neoplasia type 2B and familial medullary thyroid carcinoma. 10445857

1999
dbSNP: rs76262710
rs76262710
RET
A 0.700 CausalMutation CLINVAR Case report: a p.C618S RET proto-oncogene germline mutation in a large Chinese pedigree with familial medullary thyroid carcinoma. 22068382

2012
dbSNP: rs79658334
rs79658334
RET
A 0.700 CausalMutation CLINVAR Characterization of V804M-mutated RET proto-oncogene associated with familial medullary thyroid cancer, report of the largest Turkish family. 25501606

2015
dbSNP: rs146646971
rs146646971
RET
C 0.700 CausalMutation CLINVAR Coexistence of multiple endocrine neoplasia type 1 and type 2 in a large Italian family. 21678021

2011
dbSNP: rs79781594
rs79781594
RET
T 0.700 CausalMutation CLINVAR Diagnosis of multiple endocrine neoplasia [MEN] 2A, 2B and familial medullary thyroid cancer [FMTC] by multiplex PCR and heteroduplex analyses of RET proto-oncogene mutations. 8807338

1996
dbSNP: rs377767397
rs377767397
RET
A 0.700 CausalMutation CLINVAR Different RET gene mutation-induced multiple endocrine neoplasia type 2A in 3 Chinese families. 28099363

2017
dbSNP: rs77939446
rs77939446
RET
A 0.700 CausalMutation CLINVAR Disease-modifying polymorphisms and C609Y mutation of RET associated with high penetrance of phaeochromocytoma and low rate of MTC in MEN2A. 27994876

2016
dbSNP: rs377767397
rs377767397
RET
A 0.700 CausalMutation CLINVAR Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994-2014: A Nationwide Study. 27809725

2017
dbSNP: rs75996173
rs75996173
RET
A 0.700 CausalMutation CLINVAR Diverse phenotypes associated with exon 10 mutations of the RET proto-oncogene. 7881414

1994
dbSNP: rs75030001
rs75030001
RET
T 0.700 CausalMutation CLINVAR Failure of pentagastrin-stimulated calcitonin testing in early manifestation of familial medullary thyroid cancer. 22965292

2012