Gene: RAD50 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs778555849
rs778555849
RAD50 ; TH2LCRR
T 0.700 CausalMutation CLINVAR The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels. 28961279

2017
dbSNP: rs786201897
rs786201897
RAD50
TA 0.700 CausalMutation CLINVAR Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene. 27913932

2017
dbSNP: rs1247689593
rs1247689593
RAD50
T 0.700 CausalMutation CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949

2016
dbSNP: rs149201802
rs149201802
RAD50
G 0.700 CausalMutation CLINVAR Multigene testing of moderate-risk genes: be mindful of the missense. 26787654

2016
dbSNP: rs1554098706
rs1554098706
RAD50
CT 0.700 CausalMutation CLINVAR Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. 26824983

2016
dbSNP: rs397507178
rs397507178
RAD50
TA 0.700 CausalMutation CLINVAR Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. 26824983

2016
dbSNP: rs587782895
rs587782895
RAD50
C 0.700 CausalMutation CLINVAR Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. 26824983

2016
dbSNP: rs1060501933
rs1060501933
RAD50 ; TH2LCRR
A 0.700 GeneticVariation CLINVAR Human RAD50 makes a functional DNA-binding complex. 25828805

2015
dbSNP: rs149201802
rs149201802
RAD50
G 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs1554098706
rs1554098706
RAD50
CT 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs377260382
rs377260382
IL5 ; RAD50
A 0.700 GeneticVariation CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681

2015
dbSNP: rs377260382
rs377260382
IL5 ; RAD50
A 0.700 GeneticVariation CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658

2015
dbSNP: rs397507178
rs397507178
RAD50
TA 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs587780155
rs587780155
RAD50
A 0.700 CausalMutation CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681

2015
dbSNP: rs760146707
rs760146707
RAD50
G 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs766315644
rs766315644
RAD50
T 0.700 CausalMutation CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441

2015
dbSNP: rs786203485
rs786203485
RAD50
T 0.700 CausalMutation CLINVAR Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing. 25151137

2015
dbSNP: rs876658212
rs876658212
IL5 ; RAD50
G 0.700 GeneticVariation CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681

2015
dbSNP: rs876658212
rs876658212
IL5 ; RAD50
G 0.700 GeneticVariation CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658

2015
dbSNP: rs876658770
rs876658770
RAD50 ; TH2LCRR
T 0.700 GeneticVariation CLINVAR Human RAD50 makes a functional DNA-binding complex. 25828805

2015
dbSNP: rs1060501933
rs1060501933
RAD50 ; TH2LCRR
A 0.700 GeneticVariation CLINVAR Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. 24894818

2014
dbSNP: rs1236278956
rs1236278956
RAD50
A 0.700 GeneticVariation CLINVAR Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. 24894818

2014
dbSNP: rs149201802
rs149201802
RAD50
G 0.700 CausalMutation CLINVAR Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas. 24240112

2014
dbSNP: rs1554098706
rs1554098706
RAD50
CT 0.700 CausalMutation CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289

2014
dbSNP: rs587781355
rs587781355
RAD50
A 0.700 CausalMutation CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289

2014