Gene: SDHA ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs200397144
rs200397144
SDHA
T 0.700 GeneticVariation CLINVAR Clinical Aspects of SDHA-Related Pheochromocytoma and Paraganglioma: A Nationwide Study. 29177515

2018
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Successful response to pegylated interferon alpha in a patient with recurrent paraganglioma. 27895137

2017
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Adrenocortical carcinoma and succinate dehydrogenase gene mutations: an observational case series. 28819017

2017
dbSNP: rs200397144
rs200397144
SDHA
T 0.700 GeneticVariation CLINVAR SDHA mutated paragangliomas may be at high risk of metastasis. 28500238

2017
dbSNP: rs200397144
rs200397144
SDHA
T 0.700 GeneticVariation CLINVAR SDHA related tumorigenesis: a new case series and literature review for variant interpretation and pathogenicity. 28546994

2017
dbSNP: rs779151375
rs779151375
SDHA
G 0.700 GeneticVariation CLINVAR Clinical Characterization of the Pheochromocytoma and Paraganglioma Susceptibility Genes SDHA, TMEM127, MAX, and SDHAF2 for Gene-Informed Prevention. 28384794

2017
dbSNP: rs9809219
rs9809219
SDHA
T 0.700 GeneticVariation CLINVAR SDHA mutation with dominant transmission results in complex II deficiency with ocular, cardiac, and neurologic involvement. 27683074

2017
dbSNP: rs1061517
rs1061517
SDHA ; CCDC127
G 0.700 GeneticVariation CLINVAR Expanded genetic screening panel for the Ashkenazi Jewish population. 26334176

2016
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR In Vivo Detection of Succinate by Magnetic Resonance Spectroscopy as a Hallmark of SDHx Mutations in Paraganglioma. 26490314

2016
dbSNP: rs878854627
rs878854627
SDHA
T 0.700 CausalMutation CLINVAR Germline Variants in Targeted Tumor Sequencing Using Matched Normal DNA. 26556299

2016
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Heterogeneous genetic background of the association of pheochromocytoma/paraganglioma and pituitary adenoma: results from a large patient cohort. 25494863

2015
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR 15 YEARS OF PARAGANGLIOMA: The association of pituitary adenomas and phaeochromocytomas or paragangliomas. 26113600

2015
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR SDHA mutations causing a multisystem mitochondrial disease: novel mutations and genetic overlap with hereditary tumors. 24781757

2015
dbSNP: rs200397144
rs200397144
SDHA
T 0.700 GeneticVariation CLINVAR SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T). 25720320

2015
dbSNP: rs748089700
rs748089700
SDHA
T 0.700 CausalMutation CLINVAR SDHB/SDHA immunohistochemistry in pheochromocytomas and paragangliomas: a multicenter interobserver variation analysis using virtual microscopy: a Multinational Study of the European Network for the Study of Adrenal Tumors (ENS@T). 25720320

2015
dbSNP: rs387906780
rs387906780
SDHA
T 0.700 CausalMutation CLINVAR Analysis of all subunits, SDHA, SDHB, SDHC, SDHD, of the succinate dehydrogenase complex in KIT/PDGFRA wild-type GIST. 23612575

2014
dbSNP: rs778207102
rs778207102
SDHA
T 0.700 CausalMutation CLINVAR Succinate dehydrogenase deficient gastrointestinal stromal tumors (GISTs) - a review. 24886695

2014
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma. 23666964

2013
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors. 23730622

2013
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors. 22955521

2013
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR SDHA mutations in adult and pediatric wild-type gastrointestinal stromal tumors. 23174939

2013
dbSNP: rs142441643
rs142441643
SDHA
T 0.700 CausalMutation CLINVAR Expression of IGF-1 receptor in KIT/PDGF receptor-α wild-type gastrointestinal stromal tumors with succinate dehydrogenase complex dysfunction. 23252569

2013
dbSNP: rs1553998199
rs1553998199
SDHA
T 0.700 CausalMutation CLINVAR Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors. 22955521

2013
dbSNP: rs200397144
rs200397144
SDHA
T 0.700 GeneticVariation CLINVAR A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma. 23666964

2013
dbSNP: rs387906780
rs387906780
SDHA
T 0.700 CausalMutation CLINVAR Sequence diversity and conservation in factors influencing succinate dehydrogenase flavinylation. 23154507

2013