Gene: CDH1 ×
Source: CLINVAR ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs876660771
rs876660771
CDH1
A 0.700 CausalMutation CLINVAR A Life Potentially Saved Through Hereditary Cancer Panel Testing. 28195815

2017
dbSNP: rs878854691
rs878854691
CDH1
A 0.700 CausalMutation CLINVAR Next-generation sequencing in familial breast cancer patients from Lebanon. 28202063

2017
dbSNP: rs587780113
rs587780113
CDH1
C 0.700 CausalMutation CLINVAR Panel testing reveals nonsense and missense CDH1 mutations in families without hereditary diffuse gastric cancer. 27064202

2016
dbSNP: rs587780537
rs587780537
CDH1
A 0.700 CausalMutation CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312

2016
dbSNP: rs587780537
rs587780537
CDH1
A 0.700 CausalMutation CLINVAR Roles for E-cadherin cell surface regulation in cancer. 27582386

2016
dbSNP: rs587783048
rs587783048
CDH1
T 0.700 CausalMutation CLINVAR Prophylactic Total Gastrectomy: a Prospective Cohort Study of Long-Term Impact on Quality of Life. 27752808

2016
dbSNP: rs587783050
rs587783050
CDH1
A 0.700 CausalMutation CLINVAR Chromoendoscopy in combination with random biopsies does not improve detection of gastric cancer foci in CDH1 mutation positive patients. 27995193

2016
dbSNP: rs587783050
rs587783050
CDH1
A 0.700 CausalMutation CLINVAR Prophylactic total gastrectomy in the management of hereditary tumor syndromes. 27682646

2016
dbSNP: rs1060501244
rs1060501244
CDH1
A 0.700 CausalMutation CLINVAR Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1. 26072394

2015
dbSNP: rs1131690809
rs1131690809
CDH1
C 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer syndrome: improved performances of the 2015 testing criteria for the identification of probands with a CDH1 germline mutation. 26025002

2015
dbSNP: rs587780113
rs587780113
CDH1
C 0.700 CausalMutation CLINVAR Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300

2015
dbSNP: rs587780784
rs587780784
CDH1
T 0.700 CausalMutation CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727

2015
dbSNP: rs587780784
rs587780784
CDH1
T 0.700 CausalMutation CLINVAR Accuracy of Hereditary Diffuse Gastric Cancer Testing Criteria and Outcomes in Patients With a Germline Mutation in CDH1. 26072394

2015
dbSNP: rs587780787
rs587780787
CDH1
T 0.700 CausalMutation CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159

2015
dbSNP: rs587780787
rs587780787
CDH1
T 0.700 CausalMutation CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727

2015
dbSNP: rs587781290
rs587781290
CDH1
TA 0.700 CausalMutation CLINVAR Clinical Actionability of Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Risk Assessment. 26270727

2015
dbSNP: rs587783047
rs587783047
CDH1
T 0.700 CausalMutation CLINVAR RNA splicing. The human splicing code reveals new insights into the genetic determinants of disease. 25525159

2015
dbSNP: rs587783048
rs587783048
CDH1
T 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer: updated clinical guidelines with an emphasis on germline CDH1 mutation carriers. 25979631

2015
dbSNP: rs587783048
rs587783048
CDH1
T 0.700 CausalMutation CLINVAR Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300

2015
dbSNP: rs786201045
rs786201045
CDH1
C 0.700 CausalMutation CLINVAR Hereditary diffuse gastric cancer syndrome: improved performances of the 2015 testing criteria for the identification of probands with a CDH1 germline mutation. 26025002

2015
dbSNP: rs786203752
rs786203752
CDH1
A 0.700 CausalMutation CLINVAR Hereditary Diffuse Gastric Cancer Syndrome: CDH1 Mutations and Beyond. 26182300

2015
dbSNP: rs876658932
rs876658932
CDH1
T 0.700 CausalMutation CLINVAR Tumor genome analysis includes germline genome: are we ready for surprises? 25123297

2015
dbSNP: rs1555516200
rs1555516200
CDH1
GTT 0.700 CausalMutation CLINVAR Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study. 24389957

2014
dbSNP: rs1555516200
rs1555516200
CDH1
GT 0.700 CausalMutation CLINVAR Metastatic tumor evolution and organoid modeling implicate TGFBR2 as a cancer driver in diffuse gastric cancer. 25315765

2014
dbSNP: rs1555516200
rs1555516200
CDH1
GT 0.700 CausalMutation CLINVAR Prophylactic total gastrectomy in hereditary diffuse gastric cancer: identification of two novel CDH1 gene mutations-a clinical observational study. 24389957

2014