rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The net effects of T45G polymorphism on the MAO phenotype may be achieved by changes in the adiponectin oligomer ratio and glucose levels.
|
27236826 |
2019 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
In addition to these factors, metabolic syndrome may also be related to genetic factors, the ADIPOQ + 45T> G polymorphism has been associated with serum adiponectin levels, insulin sensitivity, and obesity, which affects adiponectin levels act as protective factor for cardiovascular disease.
|
29313754 |
2019 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
LEP rs7799039, LEPR rs1137101, and ADIPOQ rs2241766 and 1501299 Polymorphisms Are Associated With Obesity and Chemotherapy Response in Mexican Women With Breast Cancer.
|
28416193 |
2017 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The results of this meta-analysis suggest that the ADIPOQ-rs2241766 G/T polymorphism might be associated with obesity in Chinese studies but not in non-Chinese studies in adults.
|
24740426 |
2014 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
However, there is no association between rs2241766 and obesity risk.
|
25223469 |
2014 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Better-designed studies that consider confounding factors and assess larger sample sizes with a focus on ADIPOQ-rs2241766G/T polymorphisms and obesity are required in the future.
|
24740426 |
2014 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We aimed to investigate the association of 45T>G single nucleotide polymorphism (SNP) in the adiponectin gene with total adiponectin levels, insulin resistance (IR), fasting blood glucose (FBG) and other markers of obesity in non-diabetic Saudi females.
|
23958652 |
2013 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The rs2241766/rs3774261 haplotype was also associated with obesity (nominal p = 0.004).
|
19573164 |
2009 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We explored potential associations of two single nucleotide polymorphisms (SNPs) in the adiponectin gene (ADIPOQ; +45T>G, rs2241766 and +276G>T, rs1501299) with circulating total and high-molecular weight (HMW) adiponectin, insulin resistance (IR), and markers of obesity in a healthy Greek female population.
|
19755407 |
2009 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The aim of our study was to determine the frequency of single nucleotide polymorphisms (SNP) 45T>G and 276G>T of the adiponectin gene and 62G>A and -180C>G of the resistin gene in patients with obesity (OB), anorexia nervosa (AN) and in control healthy normal-weight women (NW) and to study the influence of particular genotypes on serum concentrations of these hormones and on insulin sensitivity.
|
17705672 |
2008 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Previous findings that the ADIPOQ 45T-->G variant contributes to overall fatness and abdominal obesity are confirmed.
|
17209173 |
2007 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Polymorphisms of 45T/G and 276G/T in APM1 gene are not associated with hypertension or obesity, or their clinical features in Chinese Han population.
|
16944773 |
2006 |
rs2241766
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The objective of this study was to examine the role of the adiponectin gene T45G polymorphism, located in exon 2, in PCOS, since this polymorphism has been shown to be associated with obesity and insulin resistance.
|
15178661 |
2004 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> Adiponectin rs1501</span>299 polymorphism might be a candidate gene, which determines the susceptibility to obesity.
|
31502880 |
2019 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
The present study has confirmed that ADIPOQ -3971A>G (rs822396) and +276G>T (rs1501299) polymorphism may be clinically helpful to estimate obesity and MetS risk in North Indian Punjabi population.
|
30265726 |
2018 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
Among genetic variants of the <i>ADIPOQ</i> gene +276 G>T (rs1501299) and -11377 G>C (rs266729) are the most frequently investigated polymorphisms which were described in the context of genetic conditioning for a predisposition to obesity.
|
30455545 |
2018 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
There was a direct association between the polymorphisms in LEP rs7799039 and ADIPOQ rs1501299 with overweight/obesity, and these genotypes affected the response to chemotherapeutic treatment, suggesting that an obesogenic microenvironment is more favorable for tumoral progression.
|
28416193 |
2017 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
This study suggests that ADIPOQ rs17300539 and rs1501299 are associated with risk of obesity in Caucasian ethnicity, and the rs266729 is associated with obesity risk in Asian ethnicity.
|
25223469 |
2014 |
rs1501299
|
|
|
0.060 |
GeneticVariation |
BEFREE |
We explored potential associations of two single nucleotide polymorphisms (SNPs) in the adiponectin gene (ADIPOQ; +45T>G, rs2241766 and +276G>T, rs1501299) with circulating total and high-molecular weight (HMW) adiponectin, insulin resistance (IR), and markers of obesity in a healthy Greek female population.
|
19755407 |
2009 |
rs266729
|
|
|
0.050 |
GeneticVariation |
BEFREE |
ADIPOQ G rs266729 and TNF- 308 A allele are associated with obesity, MetS/NAFLD and insulin resistance.
|
31659105 |
2020 |
rs266729
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Among genetic variants of the <i>ADIPOQ</i> gene +276 G>T (rs1501299) and -11377 G>C (rs266729) are the most frequently investigated polymorphisms which were described in the context of genetic conditioning for a predisposition to obesity.
|
30455545 |
2018 |
rs266729
|
|
|
0.050 |
GeneticVariation |
BEFREE |
However, we found an effect modification of obesity</span> on the association between the ADIPOQ rs266729 SNP and total cholesterol (P = 0.00068) only in obese participants after adjusting for age, gender, BMI, and T2D status.
|
27388775 |
2016 |
rs266729
|
|
|
0.050 |
GeneticVariation |
BEFREE |
This study suggests that ADIPOQ rs17300539 and rs1501299 are associated with risk of obesity in Caucasian ethnicity, and the rs266729 is associated with obesity risk in Asian ethnicity.
|
25223469 |
2014 |
rs266729
|
|
|
0.050 |
GeneticVariation |
BEFREE |
In conclusion, we showed family-based evidence of association of SNP rs266729 at ADIPOQ gene with traits defining obesity in Arab population.
|
23845780 |
2013 |
rs17300539
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This study suggests that ADIPOQ rs17300539 and rs1501299 are associated with risk of obesity in Caucasian ethnicity, and the rs266729 is associated with obesity risk in Asian ethnicity.
|
25223469 |
2014 |