Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs368869806
rs368869806
PTCH1
T 0.700 CausalMutation CLINVAR

dbSNP: rs1008478272
rs1008478272
MMP1 ; WTAPP1
0.010 GeneticVariation BEFREE CTSG N125S (AG) genotype was significantly more frequent among osteomyelitis patients than controls (15.5% vs. 9.4%, p = 0.014). 31647805

2019
dbSNP: rs45567233
rs45567233
CTSG
0.010 GeneticVariation BEFREE CTSG N125S (AG) genotype was significantly more frequent among osteomyelitis patients than controls (15.5% vs. 9.4%, p = 0.014). 31647805

2019
dbSNP: rs779122021
rs779122021
MMP13
0.010 GeneticVariation BEFREE CTSG N125S (AG) genotype was significantly more frequent among osteomyelitis patients than controls (15.5% vs. 9.4%, p = 0.014). 31647805

2019
dbSNP: rs20417
rs20417
PTGS2 ; PACERR
0.010 GeneticVariation BEFREE However, no significant link was found between rs20417 and susceptibility to post-traumatic osteomyelitis in this Chinese cohort. 28682162

2018
dbSNP: rs689466
rs689466
PTGS2 ; PACERR
0.010 GeneticVariation BEFREE To our knowledge, we reported for the first time that COX-2 gene polymorphism rs689466 may contribute to the increased susceptibility to post-traumatic osteomyelitis in Chinese population. 28682162

2018
dbSNP: rs1477135017
rs1477135017
RUNX2
0.010 GeneticVariation BEFREE One Caucasian family with seven affected members exhibited frequent bone fractures and florid osseous dysplasia (p.Cys356Tyr), while one Chinese family with two affected members suffered from cementoma and purulent osteomyelitis (p.Cys360Tyr). 28176803

2017
dbSNP: rs16944
rs16944
IL1B
0.010 GeneticVariation BEFREE We investigated the association of IL1RNVNTR (rs2234663) and IL1B-511C > T (rs16944) polymorphisms with osteomyelitis development in patients operated on because of bone trauma. 28682145

2017
dbSNP: rs2234663
rs2234663
IL1RN
0.010 GeneticVariation BEFREE We investigated the association of IL1RNVNTR (rs2234663) and IL1B-511C > T (rs16944) polymorphisms with osteomyelitis development in patients operated on because of bone trauma. 28682145

2017
dbSNP: rs752756474
rs752756474
IFNGR1
0.010 GeneticVariation BEFREE Heterozygous IFNGR1:p.Ile183Val (frequency 0.003%) was found to be coincidental with mycobacterial osteomyelitis. 27356097

2016
dbSNP: rs1799889
rs1799889
SERPINE1
0.010 GeneticVariation BEFREE tPA Alu (I/D) (rs4646972) and PAI-1 (4G/5G) (rs1799889) polymorphisms were studied by DNA amplification with polymerase chain reaction in 261 patients with osteomyelitis and in 299 matched blood donors. 23570848

2013
dbSNP: rs4986790
rs4986790
TLR4
0.010 GeneticVariation BEFREE Homozygotes for the TLR4 (Asp299Gly) polymorphism were significantly more frequent among the 80 osteomyelitis patients than in the 155 healthy controls (3/80, 3.8%versus 0/155, 0%; P = 0.038). 16487238

2006
dbSNP: rs4986791
rs4986791
TLR4
0.010 GeneticVariation BEFREE Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients. 16487238

2006
dbSNP: rs5743708
rs5743708
TLR2
0.010 GeneticVariation BEFREE Polymorphisms in TLR2 (Arg753Gln) and TLR4 (Asp299Gly, Thr399Ile) genes are associated with bacterial infections, we therefore studied these polymorphisms in osteomyelitis patients. 16487238

2006