Gene: OPRK1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs751416416
rs751416416
OPRK1
0.010 GeneticVariation BEFREE The AA genotype of rs4680 or A_T_C_A/ A_T_C_A (rs6269_rs4633_ rs4818_rs4680) diplotype of COMT, combined with the AG genotype of OPRM1 A118G, showed significantly increased pressure pain threshold from butorphanol. 31806881

2019
dbSNP: rs1051660
rs1051660
OPRK1
0.010 GeneticVariation BEFREE We detected significant association of the rs1051660 adjusted on metastasis and pain (<i>P</i>=0.02), no other association has been detected between the 7 polymorphisms screened and the dose of morphine needed for pain relief. 29259946

2017
dbSNP: rs6473799
rs6473799
OPRK1
0.010 GeneticVariation BEFREE In conclusion, COMT rs4680 and OPRK rs6473799 polymorphisms seem to be associated with pain sensitivity. 27061127

2016
dbSNP: rs7016778
rs7016778
OPRK1
0.010 GeneticVariation BEFREE Variability in muscle pressure pain tolerance was associated with OPRK rs7016778 and rs7824175. 23570317

2013
dbSNP: rs7824175
rs7824175
OPRK1
0.010 GeneticVariation BEFREE Variability in muscle pressure pain tolerance was associated with OPRK rs7016778 and rs7824175. 23570317

2013