Gene: ABCB1 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE The CT genotype frequency of the C3435T polymorphism (p = 0.003), the CT-GT-CT (C1236T-G2677T/A-C3435T) triple genotype (p = 0.001) and the C-G (C1236T-G2677T/A) haplotype (p = 0.030) were more common in the FMF patients. 24773260

2014
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE MDR1 gene C3435T polymorphism enacts an important role on colchicine response in FMF; good response to colchicine treatment was related to the C allele, whereas poor response was related to the T allele in FMF. 24180297

2014
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE Forty-eight Turkish patients with FMF treated with colchicine were genotyped for 3435C>T, (-)1A>G, 61A>G, 1199G>A, 1236C>T, 2677G>A, 2677G>T polymorphisms in the P-gp/MDR1 gene and 3435C>T, 1B(-392A>G), 2(15713T>C), 3(23171T>C), 12(21896C>T), 17(15615T>C) polymorphisms in the CYP3A4 gene. 23408444

2013
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE Analysis of common MDR1 (ABCB1) gene C1236T and C3435T polymorphisms in Turkish patients with familial Mediterranean fever. 22194207

2011
dbSNP: rs1045642
rs1045642
ABCB1
0.050 GeneticVariation BEFREE Our results indicate that C3435T polymorphism in exon 26 of MDR1 gene is associated with colchicine resistance in nonresponder FMF patients during the common therapy protocol. 21851199

2011
dbSNP: rs1128503
rs1128503
ABCB1
0.020 GeneticVariation BEFREE The CT genotype frequency of the C3435T polymorphism (p = 0.003), the CT-GT-CT (C1236T-G2677T/A-C3435T) triple genotype (p = 0.001) and the C-G (C1236T-G2677T/A) haplotype (p = 0.030) were more common in the FMF patients. 24773260

2014
dbSNP: rs1128503
rs1128503
ABCB1
0.020 GeneticVariation BEFREE Analysis of common MDR1 (ABCB1) gene C1236T and C3435T polymorphisms in Turkish patients with familial Mediterranean fever. 22194207

2011
dbSNP: rs1289543302
rs1289543302
ABCB1
0.010 GeneticVariation BEFREE Association analysis of three ABCB1 (MDR1) gene variants (C1236T, G2677A/T and C3435T) and their genotype/haplotype combinations with the familial Mediterranean fever. 24773260

2014
dbSNP: rs2032582
rs2032582
ABCB1
0.010 GeneticVariation BEFREE The CT genotype frequency of the C3435T polymorphism (p = 0.003), the CT-GT-CT (C1236T-G2677T/A-C3435T) triple genotype (p = 0.001) and the C-G (C1236T-G2677T/A) haplotype (p = 0.030) were more common in the FMF patients. 24773260

2014