Gene: TLR2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs5743708
rs5743708
TLR2
0.040 GeneticVariation BEFREE TLR polymorphisms in FMF: association of TLR-2 (Arg753Gln) and TLR-4 (Asp299Gly, Thre399Ile) polymorphisms and myeloid cell TLR-2 and TLR-4 expression with the development of secondary amyloidosis in FMF. 20714796

2011
dbSNP: rs5743708
rs5743708
TLR2
0.040 GeneticVariation BEFREE HSP is seen more frequently in patients with familial Mediterranean fever in which TLR-2 Arg753Gln polymorphism frequency is increased. 19597734

2010
dbSNP: rs5743708
rs5743708
TLR2
0.040 GeneticVariation BEFREE Bearing in mind the central role of TLR-2 and TLR-4 in the recognition of pathogens, we conducted this study to examine whether the TLR2-R753Q, TLR4-D299G, TLR4-T399I common polymorphisms are associated with susceptibility to familial Mediterranean fever (FMF) or affect the course of the disease. 19445990

2009
dbSNP: rs5743708
rs5743708
TLR2
0.040 GeneticVariation BEFREE The frequency of the Arg753Gln TLR2 polymorphism among the Turkish population was 6%, whereas it was 25.2% among patients with FMF (p < 0.01). 17013994

2006