Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs10763170
rs10763170
PCDH15
A 0.700 GeneticVariation GWASCAT Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma. 26029870

2015
dbSNP: rs17083838
rs17083838
CDK8
A 0.700 GeneticVariation GWASCAT Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma. 26029870

2015
dbSNP: rs2359536
rs2359536
LOC105376442
G 0.700 GeneticVariation GWASCAT Common variants at 10p12.31, 10q21.1 and 13q12.13 are associated with sporadic pituitary adenoma. 26029870

2015
dbSNP: rs12778366
rs12778366
SIRT1
0.020 GeneticVariation BEFREE The haplotype containing alleles C-A in rs12778366-rs3740051 was found to be associated with increased odds of PA development as well. 31747893

2019
dbSNP: rs12778366
rs12778366
SIRT1
0.020 GeneticVariation BEFREE The SIRT1 rs12778366 polymorphism analysis in the overall group revealed differences in the genotype distribution between patients with PA and control group subjects. 28521414

2017
dbSNP: rs3740051
rs3740051
SIRT1
0.010 GeneticVariation BEFREE Our study revealed that SIRT1 rs3740051 is associated with P</span>A recurrence and invasiveness. 31747893

2019
dbSNP: rs4746720
rs4746720
SIRT1
0.010 GeneticVariation BEFREE Our purpose was to determine if SIRT1 (rs4746720, rs3740051) genotypes have an influence on the development of pituitary adenoma (PA). 31747893

2019
dbSNP: rs104894190
rs104894190
AIP
0.010 GeneticVariation BEFREE The AIP c.911G>A: p.Arg304Gln (rs104894190) variant was detected in only two patients with functional PA: one with somatotropinoma [in 1/55 (1.8%)] and one with prolactinoma [in 1/25 (4%)]. 30461320

2018
dbSNP: rs744166
rs744166
STAT3
0.010 GeneticVariation BEFREE STAT3 rs744166 polymorphism analysis in the overall group revealed differences in the genotype distribution between patients with PA and the control groups. 28521414

2017
dbSNP: rs2959656
rs2959656
MEN1 ; MAP4K2
0.010 GeneticVariation BEFREE rs2959656, a nonsynonymous variant in MEN1, is associated with the development of clinically active PA. 27185868

2016
dbSNP: rs7131056
rs7131056
DRD2
0.010 GeneticVariation BEFREE Furthermore, rs7131056 in DRD2 contributes to either faster growth of the adenoma or reduced symptomatic presentation, allowing PAs to become larger before detection. 27185868

2016
dbSNP: rs267606573
rs267606573
AIP ; MIR6752
0.010 GeneticVariation BEFREE There was one MEN1 and three AIP mutations (p.Gln307ProfsX104, p.Pro114fsX, p.Lys241X) among pediatric patients with isolated GH- or PRL-secreting PA and one additional MEN1 mutation in a patient with positive family history. 20507346

2010