Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
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0.860 | GeneticVariation | BEFREE | In contrast, the lack of any association between rs20541 (IL13) and psoriasis in our Egyptian cohort suggests the existence of important inter-ethnic genetic differences in psoriasis susceptibility. | 25406098 | 2015 |
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G | 0.860 | GeneticVariation | GWASCAT | Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. | 25903422 | 2015 |
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G | 0.860 | GeneticVariation | GWASCAT | Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. | 26626624 | 2015 |
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0.860 | GeneticVariation | BEFREE | In subgroup analyses, the two SNPs were significantly associated (P < 0.05) with type I psoriasis, Rs495337 showed statistically difference between positive family history of psoriasis patients and controls whereas rs20541 might preferentially associated with negative family history psoriasis patients. | 23617596 | 2013 |
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0.860 | GeneticVariation | BEFREE | Evidence for an association between EBV-negative cHL and rs20541 (5q31, IL13: OR = 1.53, 95% CI = 1.32 to 1.76, P = 5.4 x 10(-9)), a variant previously linked to psoriasis and asthma, was observed; however, the evidence for replication was less clear. | 22286212 | 2012 |
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0.860 | GeneticVariation | BEFREE | The minor allele T of rs20541 in IL13 is the risk allele for asthma but the protective allele for psoriasis. | 22694930 | 2012 |
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0.860 | GeneticVariation | BEFREE | The authors genotyped three groups of Caucasians: those with PsA, those with psoriasis without arthritis (PsC) and healthy controls for the rs20541 and rs848 IL13 single nucleotide polymorphisms (SNPs). | 21613309 | 2011 |
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0.860 | GeneticVariation | GWASDB | Association analyses identify six new psoriasis susceptibility loci in the Chinese population. | 20953187 | 2010 |
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G | 0.860 | GeneticVariation | GWASDB | Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. | 19169254 | 2009 |
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G | 0.860 | GeneticVariation | GWASCAT | Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. | 19169254 | 2009 |
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0.860 | GeneticVariation | BEFREE | A multitiered genetic association study of 25 215 single-nucleotide polymorphisms (SNPs) in three case-control sample sets (1446 patients and 1432 controls) identified three IL13-linked SNPs (rs1800925, rs20541 and rs848) associated with psoriasis. | 18075513 | 2008 |