rs151340626
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CLCN5 mutation Ser244Leu is associated with X-linked renal failure without X-linked recessive hypophosphatemic rickets.
|
9452997 |
1998 |
rs151340624
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The R704X mutation is identical to that found in X-linked recessive nephrolithiasis, but there was no renal failure in our patient.
|
9893114 |
1999 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The combined effect of renal failure and a common mutation (C677T) in the methylenetetrahydrofolate reductase gene that leads to serum homocysteine elevations in dialysis patients was investigated.
|
10770966 |
2000 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
While both renal failure and mutations of the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene may result in hyperhomocysteinemia and CVD, the distinct roles of the thermolabile MTHFR mutation at nucleotide C677T and the more recently described mutation at nucleotide A1298C have not been evaluated concurrently in patients on hemodialysis.
|
12187094 |
2002 |
rs1042636
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that CaR gene polymorphism (codon G990R) influences the responsiveness of the parathyroid gland to changes of extracellular Ca2+ in ESRD patients.
|
11863123 |
2002 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
The methylenetetrahydrofolate reductase 677 C/T genotypes were determined in 174 type 2 diabetic patients: 80 with and 94 without renal failure due to diabetic nephropathy.
|
12784186 |
2003 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Homocysteine, folate, vitamin B12 levels, and C677T MTHFR mutation in children with renal failure.
|
12644913 |
2003 |
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
rs28933979
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Renal manifestations of ATTR V30M, like other amyloidoses, are different levels of proteinuria and renal insufficiency.
|
12832749 |
2003 |
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
rs867394500
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We studied retrospectively the role of angiotensinogen (AGT) M235T, angiotensin converting enzyme (ACE) insertion/deletion (I/D), angiotensin II type 1 receptor (AT1R) A1166C, aldosterone syntase (CYP11B2) -344C/T and intron 2 W/C polymorphisms in conjunction with clinical and biochemical covariables on the rate of progression of renal insufficiency in a group of patients with ESRD of various etiologies.
|
12832734 |
2003 |
rs760336723
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the data do suggest that Wt1 R394W-induced glomerulosclerosis may be independent of downregulation of the genes for NPHS1, NPHS2, CD2AP, and podocalyxin and may involve other genes yet to be implicated in renal failure.
|
15509792 |
2004 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
However, we did not prove the hypothesis that MTHFR 677C --> T influences the risk of development of renal failure in the course of hypertension.
|
16280279 |
2005 |
rs4961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism (Gly460Trp) within the alpha-adducin gene (ADD1) may influence several renal phenotypes, including salt sensitivity, susceptibility to renal failure, the renal haemodynamics and confer a worse cardiovascular risks profile.
|
16612256 |
2006 |
rs3759126
|
|
|
0.010 |
GeneticVariation |
BEFREE |
No correlation was found to exist between the AQP-2 gene polymorphism (rs3759126) and serum electrolyte levels in pre-ESRD patients (p = 0.38 for serum sodium level and p = 0.44 for serum potassium level).
|
17763164 |
2007 |
rs1801282
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy.
|
18467141 |
2008 |
rs1805192
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy.
|
18467141 |
2008 |
rs1044498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, the extensively studied K121Q variant (rs1044498) did not reveal evidence for association with type 2 diabetic ESRD in this African-American population.
|
18184924 |
2008 |
rs2032487
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Contrasting the 751 T2DM-ESRD cases with 227 T2DM non-nephropathy controls revealed that E1 haplotype SNPs rs4821480, rs2032487 and rs4821481 were associated with kidney failure (OR 1.38-1.40 recessive, all P < 0.048).
|
19567477 |
2009 |
rs121908144
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The functional consequences of p.I12T differ from BSND mutations that cause renal failure and deafness in Bartter syndrome type IV. p.I12T leaves chloride channel function unaffected and only interferes with chaperone function of barttin in intracellular trafficking.
|
19646679 |
2009 |
rs4821480
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Contrasting the 751 T2DM-ESRD cases with 227 T2DM non-nephropathy controls revealed that E1 haplotype SNPs rs4821480, rs2032487 and rs4821481 were associated with kidney failure (OR 1.38-1.40 recessive, all P < 0.048).
|
19567477 |
2009 |
rs4821481
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Contrasting the 751 T2DM-ESRD cases with 227 T2DM non-nephropathy controls revealed that E1 haplotype SNPs rs4821480, rs2032487 and rs4821481 were associated with kidney failure (OR 1.38-1.40 recessive, all P < 0.048).
|
19567477 |
2009 |
rs1217691063
|
|
|
0.080 |
GeneticVariation |
BEFREE |
Obtained results indicate that C677T polymorphism is not associated with onset, duration and cause of kidney failure in our hemodialysis population.
|
20433440 |
2010 |
rs11739136
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Common KCNMB1 gain-of-function variant Glu65Lys influences GFR, and 65Lys carriers exhibit not only elevated baseline GFR, but also more rapid GFR decline (and consequent development of renal failure) in CKD.
|
20861615 |
2010 |
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The paraoxonase (PON1) polymorphisms, Leu55Met and Gln192Arg, modulate intima-medial artery thickening, prognosis of cardiovascular stroke, and renal failure in other diseases.
|
20639675 |
2010 |