|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
The variant T of C677T was identified in 60.65% of RVO</span> patients and 59.10% of control subjects, while the variant C of A1298C was present in 46.45% of RVO patients and 51.14% of controls.
|
31418317 |
2019 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Two RVO patients (4.1%) with bilateral involvement had MTHFR C677T mutation.
|
28085519 |
2017 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no evidence to suggest an association between homozygosity for the MTHFR C677T genotype and RVO.
|
25428529 |
2014 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Association of methylenetetrahydrofolate reductase (A1298C and C677T) polymorphisms with retinal vein occlusion in Tunisian patients.
|
24440586 |
2014 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Our results suggest that there may be an association between increased risk for RVO and ACE I/D, MTHFR C677T, PAI-1 4G/5G and factor V Leiden polymorphisms, whereas the Val34Leu variant may exert a protective effect.
|
23289804 |
2013 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
our study suggests that HHcy is a possible risk factor for RVT development, while no association was found between RVT and the C677T MTHFR genotype.
|
19825913 |
2010 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
There was no evidence of association between homozygosity for the MTHFR C677T genotype and RVO (odds ratio [OR] 1.20; 95% CI, 0.84-1.71), but again marked heterogeneity (P = 0.004, I(2) = 53%) was observed.
|
19729099 |
2009 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
A prevalence of up to 30% of fasting hyperhomocysteinemia has been recently reported in patients with retinal vein occlusion (RVO) whereas conflicting data exist on the role of C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) gene as a risk factor for RVO.
|
12877902 |
2003 |
|
rs1217691063
|
|
|
0.090 |
GeneticVariation |
BEFREE |
Our data suggests that homozygosity for the MTHFR C677T polymorphism is a risk factor of RVO in addition to arterial hypertension and a family history of stroke.
|
9863710 |
1998 |
|
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Two RVO patients (4.1%) with bilateral involvement had MTHFR C677T mutation.
|
28085519 |
2017 |
|
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Our results suggest that there may be an association between increased risk for RVO and ACE I/D, MTHFR C677T, PAI-1 4G/5G and factor V Leiden polymorphisms, whereas the Val34Leu variant may exert a protective effect.
|
23289804 |
2013 |
|
rs1188383936
|
|
|
0.030 |
GeneticVariation |
BEFREE |
This study therefore aimed to establish the prevalence of the GpIa/IIa polymorphisms and the three commonest hereditary thrombophilic disorders (prothrombin gene G20210A (PT) mutation, Factor V Leiden (FVL), and the thermolabile methylene tetrahydrofolate reductase C677T (MTHFR) mutation) in patients with RVO and normal controls.
|
12928694 |
2003 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The variant T of C677T was identified in 60.65% of RVO patients and 59.10% of control subjects, while the variant C of A1298C was present in 46.45% of RVO patients and 51.14% of controls.
|
31418317 |
2019 |
|
rs763351020
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In our study, the FII G20210A and the MTHFR C677T mutations resulted significantly higher in patients than in controls; in contrast, thrombophilic mutation of FV, ACE, and PAI-1 genes was not statistically correlated with RVO.
|
24569626 |
2015 |
|
rs397507444
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Association of methylenetetrahydrofolate reductase (A1298C and C677T) polymorphisms with retinal vein occlusion in Tunisian patients.
|
24440586 |
2014 |
|
rs763351020
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Our results suggest that there may be an association between increased risk for RVO and ACE I/D, MTHFR C677T, PAI-1 4G/5G and factor V Leiden polymorphisms, whereas the Val34Leu variant may exert a protective effect.
|
23289804 |
2013 |
|
rs751377893
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant differences were found in the frequencies of the genotypes for both the FVL (G1691A) (P<10(-3), odds ratio [OR]=17.4, confidence interval [CI]=6.20-59) and prothrombin (G20210A) (P=.007, OR=5.11, CI=1.30-29) polymorphisms between RVO patients and healthy controls.
|
24630828 |
2014 |
|
rs899127658
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant differences were found in the frequencies of the genotypes for both the FVL (G1691A) (P<10(-3), odds ratio [OR]=17.4, confidence interval [CI]=6.20-59) and prothrombin (G20210A) (P=.007, OR=5.11, CI=1.30-29) polymorphisms between RVO patients and healthy controls.
|
24630828 |
2014 |
|
rs144246695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results suggest that there may be an association between increased risk for RVO and ACE I/D, MTHFR C677T, PAI-1 4G/5G and factor V Leiden polymorphisms, whereas the Val34Leu variant may exert a protective effect.
|
23289804 |
2013 |
|
rs662
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To determine if the paraoxonase 1 L55M and paraoxonase 1 Q192R gene polymorphisms have an effect on the risk of having a retinal vein occlusion (RVO).
|
23441121 |
2013 |
|
rs854560
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Protective effect of paraoxonase 1 gene variant L55M in retinal vein occlusion.
|
23441121 |
2013 |
|
rs9923231
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Vitamin K epoxide reductase recycles reduced vitamin K, which is essential for the gamma carboxylation of clotting factors II, VII, IX, X and proteins C and S. Recently, the vitamin K epoxide reductase complex subunit 1 (VKORC1) -1639G>A (rs9923231) polymorphism has been reported as a novel risk factor for RVO in a Turkish population.
|
23972066 |
2013 |
|
rs1799983
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We investigated haemorheological variables in patients with idiopathic sudden sensorineural hearing loss (ISSHL), retinal vein occlusion (RVO) and systemic sclerosis (SSc), as possible models of microvascular damage, and their relationship with eNOS gene T-786C, G894T and 4a/4b polymorphisms.
|
17634663 |
2007 |
|
rs77375493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Conventional diagnostic criteria for myeloproliferative disorders and the JAK2 V617F mutation (which is strongly associated with myeloproliferative disorders) were assessed in RVO patients showing EECs.
|
18054634 |
2007 |
|
rs566289099
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The possible interaction of factors contributing to RVO in conjunction with the Thr377Met mutation warrants further investigation.
|
15823921 |
2005 |