Gene: NRGN ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs55661361
rs55661361
NRGN
G 0.700 GeneticVariation GWASCAT Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect. 30285260

2019
dbSNP: rs55661361
rs55661361
NRGN
A 0.700 GeneticVariation GWASCAT Identification of common genetic risk variants for autism spectrum disorder. 30804558

2019
dbSNP: rs55661361
rs55661361
NRGN
0.700 GeneticVariation GWASCAT Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways. 31374203

2019
dbSNP: rs55661361
rs55661361
NRGN
0.700 GeneticVariation GWASCAT Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study. 31268507

2019
dbSNP: rs12293670
rs12293670
NRGN
0.700 GeneticVariation GWASCAT Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection. 29483656

2018
dbSNP: rs55661361
rs55661361
NRGN
G 0.700 GeneticVariation GWASCAT Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia. 28991256

2017
dbSNP: rs55661361
rs55661361
NRGN
0.700 GeneticVariation GWASCAT Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia. 28540026

2017
dbSNP: rs55661361
rs55661361
NRGN
G 0.700 GeneticVariation GWASCAT Genome-wide association study of schizophrenia in Ashkenazi Jews. 26198764

2015
dbSNP: rs55661361
rs55661361
NRGN
G 0.700 GeneticVariation GWASCAT Biological insights from 108 schizophrenia-associated genetic loci. 25056061

2014
dbSNP: rs12278912
rs12278912
NRGN
0.030 GeneticVariation BEFREE The "GA" haplotype of rs7113041-rs12278912 was significantly associated with schizophrenia, major depressive disorder and bipolar disorder (corresponding P values were 2.85E-04, 3.00E-03, and 5.40E-04 after Bonferroni correction). 26828755

2016
dbSNP: rs12278912
rs12278912
NRGN
0.030 GeneticVariation BEFREE After applying Bonferroni correction for 13 genotype measures and setting P-values for significance (P<0.0039; 0.05/13), three effects remained significant: the rs12807809-rs12278912 diplotype-diagnosis interactions on performance intelligence quotient (CG/CG: P=3.9 × 10(-13); TA/TA: P=1.1 × 10(-7)) and TA/TA diplotype on performance intelligence quotient in patients with schizophrenia (P=8.2 × 10(-8)) remained significant. 23903071

2013
dbSNP: rs12278912
rs12278912
NRGN
0.030 GeneticVariation BEFREE This study provides further evidence of the association of the NRGN gene with schizophrenia, and our results suggest that there is a link between the TG haplotype of rs12807809-rs12278912, decreased expression of NRGN and risk of developing schizophrenia. 22461181

2012
dbSNP: rs7113041
rs7113041
NRGN
0.020 GeneticVariation BEFREE The "GA" haplotype of rs7113041-rs12278912 was significantly associated with schizophrenia, major depressive disorder and bipolar disorder (corresponding P values were 2.85E-04, 3.00E-03, and 5.40E-04 after Bonferroni correction). 26828755

2016
dbSNP: rs7113041
rs7113041
NRGN
0.020 GeneticVariation BEFREE Genotype distribution showed association of the rs7113041 SNP with schizophrenia in males of Portuguese origin, which was confirmed by the analysis of the proband-parent triads. 17140601

2008