|
rs10490175
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
rs10490162
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on previous suggestive evidence of an impact on clozapine response in patients with schizophrenia, we conducted an association study of NRXN1 polymorphisms (rs12467557 and rs10490162) with antipsychotic treatment response in 54 patients with schizophrenia in a double blind, placebo-controlled NIMH inpatient crossover trial and examined for association with risk for schizophrenia in independent case-control and family-based clinical cohorts.
|
24633560 |
2014 |
|
rs12467557
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Based on previous suggestive evidence of an impact on clozapine response in patients with schizophrenia, we conducted an association study of NRXN1 polymorphisms (rs12467557 and rs10490162) with antipsychotic treatment response in 54 patients with schizophrenia in a double blind, placebo-controlled NIMH inpatient crossover trial and examined for association with risk for schizophrenia in independent case-control and family-based clinical cohorts.
|
24633560 |
2014 |
|
rs1045881
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1045881 variant was not significantly associated with schizophrenia (N=302 case-control pairs), but with clozapine response (N=163; p=0.030).
|
21890328 |
2011 |
|
rs10490168
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed that four SNPs of NRXN1 gene were significantly associated with schizophrenia (rs10490168: G > A, p = 0.017; rs2024513: A > G, p = 0.006; rs13382584: T > C, p = 0.009; and rs1558852: G > A, p = 0.031).
|
21477380 |
2011 |
|
rs112638127
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Since I1068V was observed in a single patient, it is impossible to exclude the possibility that I1068V makes a minor contribution to schizophrenia susceptibility.
|
21288692 |
2011 |
|
rs13382584
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed that four SNPs of NRXN1 gene were significantly associated with schizophrenia (rs10490168: G > A, p = 0.017; rs2024513: A > G, p = 0.006; rs13382584: T > C, p = 0.009; and rs1558852: G > A, p = 0.031).
|
21477380 |
2011 |
|
rs1558852
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed that four SNPs of NRXN1 gene were significantly associated with schizophrenia (rs10490168: G > A, p = 0.017; rs2024513: A > G, p = 0.006; rs13382584: T > C, p = 0.009; and rs1558852: G > A, p = 0.031).
|
21477380 |
2011 |
|
rs2024513
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results showed that four SNPs of NRXN1 gene were significantly associated with schizophrenia (rs10490168: G > A, p = 0.017; rs2024513: A > G, p = 0.006; rs13382584: T > C, p = 0.009; and rs1558852: G > A, p = 0.031).
|
21477380 |
2011 |