Significance correlation was observed between rs2232618 and risk of sepsis in Southwest patients (<i>P</i> = 0.002 for the dominant model, <i>P</i> = 0.006 for the recessive model).
To determine whether the genotype frequencies of the five bi-allelic polymorphisms in the bactericidal/permeability increasing protein (BPI) (Lys216 --> Glu; PstI polymorphism in intron 5; silent mutation G545 --> C) and the lipopolysaccharide binding protein (LBP) (Cys98 --> Gly; Pro436 --> Leu) are associated with the incidence and lethality of sepsis.