| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.010 | GeneticVariation | BEFREE | The rs12812500 variant of the <i>CPM</i> gene may increase silicosis susceptibility by affecting the expression of <i>CPM</i>, which may contribute to silicosis susceptibility with biological plausibility. | 30674606 | 2019 |
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0.010 | GeneticVariation | BEFREE | We systematically screened eight potentially functional single-neucleotide polymorphism (SNPs) in the genes near rs73329476 (carboxypeptidase M (<i>CPM</i>) and cleavage and polyadenylation specific factor 6 (<i>CPSF6</i>)) in a case-control study including 177 cases with silicosis and 204 healthy controls, matched to cases with years of silica dust exposure. | 30674606 | 2019 |
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|
0.010 | GeneticVariation | BEFREE | We systematically genotyped 8 potentially functional SNPs and the previously reported rs2076295 and rs2744371 in DSP gene region and evaluated the associations between these 10 SNPs and silicosis risk in a case-control study that included 177 silicosis cases and 204 controls with similar numbers of silica dust exposure years as the cases from a Chinese population. | 30207747 | 2018 |
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|
0.010 | GeneticVariation | BEFREE | The rs2076304 in DSP gene is associated with a significantly increased risk of silicosis in a Han Chinese population. | 30207747 | 2018 |
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0.010 | GeneticVariation | BEFREE | These results indicate that rs2609255 may modify silicosis susceptibility in the Chinese population. | 29621588 | 2018 |
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|
0.010 | GeneticVariation | BEFREE | We systematically genotyped 8 potentially functional SNPs and the previously reported rs2076295 and rs2744371 in DSP gene region and evaluated the associations between these 10 SNPs and silicosis risk in a case-control study that included 177 silicosis cases and 204 controls with similar numbers of silica dust exposure years as the cases from a Chinese population. | 30207747 | 2018 |
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|
0.010 | GeneticVariation | BEFREE | No association of other polymorphisms (NRAMP1 D543N, TNF-alpha-308) and susceptibility to silicosis or PTB in Chinese miners was found. | 17223386 | 2007 |