Gene: ANTXR2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4333130
rs4333130
ANTXR2
0.820 GeneticVariation BEFREE The association between ANTXR2 rs4333130 and AS was independent of HLA-B27 status. 26590821

2016
dbSNP: rs4333130
rs4333130
ANTXR2
0.820 GeneticVariation BEFREE The strongest haplotype association was observed with rs4690127-rs6823031-rs4333130 (P = 2.5 × 10(-4)). rs6534639 and rs4333130 showed a cis-interaction (P = 0.027) in AS. 26728147

2016
dbSNP: rs4333130
rs4333130
ANTXR2
0.820 GeneticVariation GWASDB Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010
dbSNP: rs4333130
rs4333130
ANTXR2
0.820 GeneticVariation GWASCAT Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. 20062062

2010
dbSNP: rs4389526
rs4389526
ANTXR2
0.810 GeneticVariation BEFREE Taken together, this study shows no association between ANTXR2 polymorphisms and AS susceptibility in a Chinese Han population, but meta-analysis showed that rs4389526 in the ANTXR2 gene was weakly associated with AS susceptibility in both Caucasian and Chinese Han patients. 30255098

2018
dbSNP: rs4389526
rs4389526
ANTXR2
A 0.810 GeneticVariation GWASCAT Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. 21743469

2011
dbSNP: rs4389526
rs4389526
ANTXR2
A 0.810 GeneticVariation GWASDB Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility. 21743469

2011
dbSNP: rs11098964
rs11098964
ANTXR2
0.700 GeneticVariation GWASCAT Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci. 26974007

2016
dbSNP: rs6534639
rs6534639
ANTXR2
0.020 GeneticVariation BEFREE Results showed a weak association of rs4389526 with AS susceptibility in all studies but failed to show an association of rs6534639 with AS in Chinese Han. 30255098

2018
dbSNP: rs6534639
rs6534639
ANTXR2
0.020 GeneticVariation BEFREE The strongest haplotype association was observed with rs4690127-rs6823031-rs4333130 (P = 2.5 × 10(-4)). rs6534639 and rs4333130 showed a cis-interaction (P = 0.027) in AS. 26728147

2016
dbSNP: rs12504282
rs12504282
ANTXR2
0.010 GeneticVariation BEFREE Among the 16 AS-associated variants, rs30187 showed weaker risk effect while rs10050860 and rs12504282 seemed to attribute more risk in Han Chinese than Caucasians. 31523044

2019
dbSNP: rs4690127
rs4690127
ANTXR2
0.010 GeneticVariation BEFREE The strongest haplotype association was observed with rs4690127-rs6823031-rs4333130 (P = 2.5 × 10(-4)). rs6534639 and rs4333130 showed a cis-interaction (P = 0.027) in AS. 26728147

2016
dbSNP: rs6823031
rs6823031
ANTXR2
0.010 GeneticVariation BEFREE The strongest haplotype association was observed with rs4690127-rs6823031-rs4333130 (P = 2.5 × 10(-4)). rs6534639 and rs4333130 showed a cis-interaction (P = 0.027) in AS. 26728147

2016