rs1860545
|
|
|
0.700 |
GeneticVariation |
GWASCAT |
Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci.
|
26974007 |
2016 |
rs1860545
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Identification of multiple risk variants for ankylosing spondylitis through high-density genotyping of immune-related loci.
|
23749187 |
2013 |
rs4149570
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We replicated associations between AS and the polymorphisms in TNF (rs1800629), TNFRSF1A (rs4149570), and IL23R (rs11209026).
|
30208882 |
2018 |
rs767455
|
|
|
0.020 |
GeneticVariation |
BEFREE |
A subset of 50 AS patients was also studied for the association of these polymorphisms with the short- and long-term response to etanercept assessed by Assessment in Ankylosing Spondylitis 20 (ASAS20) and Assessment in Ankylosing Spondylitis 40 (ASAS40).Our data showed that rs767455 was associated with the susceptibility of AS, G allele of rs767455 exhibited an association with the risk of developing AS (OR = 1.63 (1.04-2.55), P = .032).
|
30075559 |
2018 |
rs4149570
|
|
|
0.020 |
GeneticVariation |
BEFREE |
NLRP3 and TFRSF1A (rs4149570) are associated with AS susceptibility.
|
28116820 |
2017 |
rs767455
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The aim of the present study was to examine the role of the polymorphisms 36A>G (TNFR1), 676T>G (TNFR2), -857C>T (TNF-alpha), -308G>A (TNF-alpha), and -238G>A (TNF-alpha) in AS susceptibility.
|
19772798 |
2009 |
rs1800693
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic polymorphism (rs1800693) of TNFRSF1A (type 1 tumour necrosis factor receptor) encodes a potentially anti-inflammatory soluble truncated form of the p55 receptor, which is associated with predisposition to multiple sclerosis but protection against ankylosing spondylitis (AS).
|
29535371 |
2019 |
rs2234649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our analysis showed that the rs2234649 polymorphism does not increase ankylosing spondylitis risk.
|
28363009 |
2017 |
rs4149577
|
|
|
0.010 |
GeneticVariation |
BEFREE |
SNPs in TNFRSF1A (rs4149577, p = 8.2 × 10⁻⁴), STAT3 (rs2293152, p = 0.0015; rs1053005, p = 0.017) and ERAP1 (rs27038, p = 0.0091; rs27037, p = 0.0092) were significantly associated with AS in Han Chinese.
|
21068102 |
2011 |