Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
---|---|---|---|---|---|---|---|---|---|---|
|
0.850 | GeneticVariation | BEFREE | In HDAC9 SNP rs2107595 risk allele-positive LVAS patients, there were 155 genes differentially expressed compared to risk allele-negative patients (fold change > ;1.2;, p < 0.05). | 29651704 | 2019 |
||||
|
0.850 | GeneticVariation | BEFREE | Results- Targeted resequencing of the <i>HDAC9</i> locus in patients with atherosclerotic stroke and controls supported candidacy of rs2107595 as the causative single nucleotide polymorphism. | 31500558 | 2019 |
||||
|
0.850 | GeneticVariation | BEFREE | Apolipoprotein L1 (APOL1) rs73885319 (OR = 1.52; CI: 1.09-2.13, P-value = .013), rs2383207 in CDKN2A/CDKN2B (OR = 3.08; CI: 1.15-8.26, P -value = .026) and rs2107595 (OR = 1.70; CI: 1.12-2.60, P-value = .014) and rs28688791 (OR = 1.52; CI: 1.03-2.26, P-value = .036) in HDAC9 gene were associated with SVD stroke at 0.05 significance level. | 28975602 | 2018 |
||||
|
0.850 | GeneticVariation | GWASCAT | Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes. | 29531354 | 2018 |
||||
|
0.850 | GeneticVariation | BEFREE | Our results revealed statistically significant associations of the rs2107595 (T/C) polymorphism with an increased risk of stroke in the allele, codominant and dominant models. | 28145521 | 2017 |
||||
|
0.850 | GeneticVariation | BEFREE | We further performed detailed plaque phenotyping and genotyping of rs2107595, the lead single-nucleotide polymorphism for large-vessel stroke, in carotid endarterectomy samples of 1858 subjects from the Athero-Express study. | 25388417 | 2015 |
||||
|
A | 0.850 | GeneticVariation | GWASDB | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. | 23041239 | 2012 |
|||
|
A | 0.850 | GeneticVariation | GWASCAT | Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies. | 23041239 | 2012 |