|
rs1531554
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.
|
28081371 |
2017 |
|
rs60249166
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.
|
28081371 |
2017 |
|
rs73271865
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.
|
28081371 |
2017 |
|
rs73460075
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
GWAS Identifies New Loci for Painful Temporomandibular Disorder: Hispanic Community Health Study/Study of Latinos.
|
28081371 |
2017 |
|
rs1676303
|
|
|
0.020 |
GeneticVariation |
BEFREE |
For the ESRRB (rs1676303) gene, an association was observed between the CC (cytosine/cytosine) genotype and the presence of articular TMDs associated with other chronic arthralgia (P = .02).
|
29175417 |
2018 |
|
rs1676303
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The rs1676303 TT (P=0.02) and rs6574293 GG (P=0.04) genotypes were associated with RCD and TMD, respectively.
|
26584852 |
2016 |
|
rs1042713
|
|
|
0.010 |
GeneticVariation |
BEFREE |
With respect to the ADRB2 gene, the non-polymorphic AA genotype in the rs1042713 region was more prevalent in the articular TMD group than in the muscular TMD group (P= 0.05).
|
31285095 |
2020 |
|
rs9332377
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TT genotype for the COMT rs9332377 gene was highly associated with the presence of muscular TMD (P= 0.03).
|
31285095 |
2020 |
|
rs1042173
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In 5HTT, the rs1042173 was associated with painful TMD (arthralgia and myofascial pain) (OR<sub>c</sub> = 1.97; CI 95%: 1.02-3.77; P = 0.04).
|
30811655 |
2019 |
|
rs13078961
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A single-nucleotide polymorphism on chromosome 3 (rs13078961) was significantly associated with TMD in males only (odds ratio = 2.9, 95% confidence interval: 2.02-4.27, P = 2.2 × 10).
|
30431558 |
2019 |
|
rs4818
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Polymorphisms in COMT rs4818 were significantly associated with myofascial pain (OR<sub>c</sub> = 2.15; CI 95%: 1.08-4.29; P = 0.02) and were borderline for painful TMD (OR<sub>c</sub> = 1.85; CI 95%: 0.97-3.51; P = 0.06) and disc displacement (OR<sub>c</sub> = 2.42; CI 95%: 1.00-5.87; P = 0.05).
|
30811655 |
2019 |
|
rs909253
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The purpose of this study was to evaluate the correlation between TNF-β +252A/G (rs909253) variant and susceptibility to TMD in a Turkish cohort.
|
30129153 |
2019 |
|
rs2273206
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The TT (timin/timin) genotype for the ESR1 (rs2273206) gene was strongly associated with the risk of developing muscle TMDs and temporomandibular joint pain (P = .04).
|
29175417 |
2018 |
|
rs165774
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site.
|
27792797 |
2017 |
|
rs6269
|
|
|
0.010 |
GeneticVariation |
BEFREE |
AA genotype of rs165774 could be a significant risk factor for the development of TMD and TMD pain, while AA genotype of rs6269 presents less postoperative chronic TMD pain and acute pain at a dental extraction site.
|
27792797 |
2017 |
|
rs1800629
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This study presents an unprecedented association between the TNFA-308 (rs1800629) polymorphism and TMD.
|
27131251 |
2016 |
|
rs6574293
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The rs1676303 TT (P=0.02) and rs6574293 GG (P=0.04) genotypes were associated with RCD and TMD, respectively.
|
26584852 |
2016 |
|
rs858339
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In addition, we have identified TT genotype of SNP rs858339 (ENPP1 gene) as a protective factor against TMD in a population of patients with dentofacial deformities.
|
27519661 |
2016 |
|
rs1200746244
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results show that the COMT rs4680 (val(158)met) polymorphism is most strongly associated with outcome measures, such that individuals with the minor A allele (met) exhibit reduced COMT activity, increased TMD risk, and increased musculoskeletal pain.
|
25218601 |
2014 |
|
rs165656
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After the False Discovery Rate (FDR) correction rs165656 remained significantly associated with TMD (P=0.049).
|
23446089 |
2014 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results show that the COMT rs4680 (val(158)met) polymorphism is most strongly associated with outcome measures, such that individuals with the minor A allele (met) exhibit reduced COMT activity, increased TMD risk, and increased musculoskeletal pain.
|
25218601 |
2014 |
|
rs4680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Results show that the COMT rs4680 (val(158)met) polymorphism is most strongly associated with outcome measures, such that individuals with the minor A allele (met) exhibit reduced COMT activity, increased TMD risk, and increased musculoskeletal pain.
|
25218601 |
2014 |
|
rs758537709
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A novel A-band titin mutation, c.92167C>T (p.P30723S), was found in 1 patient, and 1 Portuguese patient with a severe TMD phenotype proved to be homozygous for the previously reported Iberian TMD mutation.
|
24395473 |
2014 |
|
rs5993882
|
|
|
0.010 |
GeneticVariation |
BEFREE |
In subjects without depressive symptoms, rs5993882 was identified as the SNP most likely to be related to TMD pain.
|
22337325 |
2012 |
|
rs2241719
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Interactions were observed between TGFβ1 and IL-8 SNPs: an additional copy of the TGFβ1 rs2241719 minor T allele was associated with twice the odds of TMD+WPT among individuals homozygous for the IL-8 rs4073 major A allele, and half the odds of TMD+WPT among individuals heterozygous for rs4073.
|
22000099 |
2011 |