|
rs6570507
|
|
|
0.030 |
GeneticVariation |
BEFREE |
To ensure the association of rs6570507 with AIS, we conducted a meta-analysis using eight cohorts from East Asia, Northern Europe and USA.
|
30069010 |
2018 |
|
rs6570507
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Allele C of rs9403380, allele G of rs6570507, and allele A of rs7774095 can significantly add to the risk of AIS with an odds ratio of 1.17, 1.16, and 1.15, respectively.
|
28198779 |
2017 |
|
rs6570507
|
|
|
0.030 |
GeneticVariation |
BEFREE |
We provided evidence for strong association of three intronic SNPs of the GPR126 gene with AIS susceptibility: rs6570507 A > G (p =0 .0035, OR = 1.729), rs7774095 A > C (p = 0.0078, OR = 1.687), and rs7755109 A > G (p = 0.0078, OR = 1.687).
|
25479386 |
2015 |
|
rs7774095
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Allele C of rs9403380, allele G of rs6570507, and allele A of rs7774095 can significantly add to the risk of AIS with an odds ratio of 1.17, 1.16, and 1.15, respectively.
|
28198779 |
2017 |
|
rs7774095
|
|
|
0.020 |
GeneticVariation |
BEFREE |
We provided evidence for strong association of three intronic SNPs of the GPR126 gene with AIS susceptibility: rs6570507 A > G (p =0 .0035, OR = 1.729), rs7774095 A > C (p = 0.0078, OR = 1.687), and rs7755109 A > G (p = 0.0078, OR = 1.687).
|
25479386 |
2015 |
|
rs41289839
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Linkage disequilibrium analysis suggests that rs41289839 and other AIS-related SNPs were in strong LD.
|
30886859 |
2019 |
|
rs9403380
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Allele C of rs9403380, allele G of rs6570507, and allele A of rs7774095 can significantly add to the risk of AIS with an odds ratio of 1.17, 1.16, and 1.15, respectively.
|
28198779 |
2017 |
|
rs7755109
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although intronic SNPs associated with AIS didn't influence GPR126 mRNA alternative splicing, there was a strong association of rs7755109 A > G with decreased GPR126 mRNA level and protein levels.
|
25479386 |
2015 |