|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The eNOS G894T, T-786C and intron4ba polymorphisms are not associated with vasculitis.
|
26016759 |
2015 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This meta-analysis does not show that the PTPN22 C1858T polymorphism is associated with vasculitis susceptibility, but does show that this polymorphism is associated with susceptibility to AAV, WG, and ANCA status in WG.
|
22696186 |
2012 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
To assess the possible association between the PTPN22 gene 1858C-->T polymorphism and the susceptibility to Henoch-Schönlein purpura (HSP) and determine if this polymorphism is implicated in the severity of this systemic vasculitis.
|
18078626 |
2008 |
|
rs1799983
|
|
|
0.020 |
GeneticVariation |
BEFREE |
Significant differences in Glu298Asp genotype frequencies were found between the BD or vasculitis groups and the controls (BD group v controls: p(corr)=0.006; vasculitis group v controls: p<0.001).
|
14583572 |
2003 |
|
rs16925200
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Outside the HLA region, we identified the <i>KDM4C</i> gene as a common risk <i>locus</i> for vasculitides (highest peak rs16925200, P=6.23E-07, OR=1.75).
|
29374629 |
2018 |
|
rs16972959
|
|
|
0.010 |
GeneticVariation |
BEFREE |
On the other hand, SNP rs16972959 of PRKCB was found to have suggestive significant associations with vasculitis (P = 0.00718) of SLE.
|
29297929 |
2018 |
|
rs1799969
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the K469E polymorphism is associated with susceptibility to vasculitis, and that the G241R polymorphism is associated with susceptibility to BD and RA.
|
27894415 |
2016 |
|
rs5498
|
|
|
0.010 |
GeneticVariation |
BEFREE |
This meta-analysis suggests that the K469E polymorphism is associated with susceptibility to vasculitis, and that the G241R polymorphism is associated with susceptibility to BD and RA.
|
27894415 |
2016 |
|
rs3788013
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of variant genotype AC of rs3788013 was associated with the phenotype of vasculitis (p=0.012).
|
25843625 |
2015 |
|
rs1222213359
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis showed no association between vasculitis and the VEGF -1154 A/G and 2578 A/C polymorphisms.
|
24607726 |
2014 |
|
rs61752717
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We observed that in children severe phenotypes with polyserositis, erysipelas-like erythema, splenomegaly, and vasculitis are associated with high penetrance of exon 10 mutations, particularly M694V.
|
23907647 |
2014 |
|
rs2298804
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Although we did not find any significant correlation between the rs2298804 and the incidence of lupus nephritis, rs2298804 seemed to protect against proteinunia, fever and hypocomplementaemia in patients with SLE, but appeared to be a risk factor for photosensitivity and vasculitis.
|
23621092 |
2013 |
|
rs4986790
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Meta-analysis of six studies showed a significant association between the Gly/Gly+Gly/Asp genotype of the TLR4 Asp299Gly polymorphism and vasculitis and GCA (Odds ratio [OR] = 1.368, 95 % confidence interval [CI] = 1.300-1.815, p = 0.030; OR = 1.523, 95 % CI = 1.099-2.112, p = 0.012).
|
23065292 |
2013 |
|
rs4986791
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were three studies on the TLR2 Arg753Gln polymorphism and two on the TLR4 Thr399Ile polymorphism; no association with vasculitis was evident.
|
23065292 |
2013 |
|
rs5743708
|
|
|
0.010 |
GeneticVariation |
BEFREE |
There were three studies on the TLR2 Arg753Gln polymorphism and two on the TLR4 Thr399Ile polymorphism; no association with vasculitis was evident.
|
23065292 |
2013 |
|
rs1805094
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Lys656Asn SNP in the LEPR gene showed a significant but contrasting association with these vasculitides.
|
21664965 |
2012 |
|
rs4639966
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the SNP rs4639966 of 11q23.3 with SLE of age at diagnosis <20 years (OR = 1.18, p = 0.0049), malar rash (OR = 1.13, p = 0.01) and vasculitis (OR = 1.17, p = 0.02).
|
23002088 |
2012 |
|
rs6822844
|
|
|
0.010 |
GeneticVariation |
BEFREE |
To assess the influence of the interleukin (IL)2-IL21 rs6822844 G/T polymorphism in the susceptibility to biopsy-proven giant cell arteritis (GCA) and in the clinical spectrum of manifestations of this vasculitis.
|
21269573 |
2011 |
|
rs10036748
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively.
|
20516000 |
2010 |
|
rs10847697
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively.
|
20516000 |
2010 |
|
rs13385731
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively.
|
20516000 |
2010 |
|
rs4917014
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively.
|
20516000 |
2010 |
|
rs6590330
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Significant associations were found for the single nucleotide polymorphism rs10036748 of TNIP1 with photosensitivity (odds ratio (OR) = 0.87, p = 0.01) and vasculitis (OR = 1.18, p = 0.04); rs10847697 of SLC15A4 with discoid rash (OR = 1.18, p = 0.02); rs6590330 of ETS1 with SLE of age at diagnosis <20 years (OR = 1.24, p = 8.91 x 10(-5)); rs13385731 of RasGRP3 with malar rash (OR = 1.20, p = 0.01), discoid rash (OR = 0.78, p = 0.02) and ANA (OR = 0.72, p = 0.004); rs4917014 of IKZF1 with renal nephritis (OR = 1.13, p = 0.02) and malar rash (OR = 0.83, p = 0.00038), respectively.
|
20516000 |
2010 |
|
rs1195782955
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.
|
16792675 |
2006 |
|
rs3743930
|
|
|
0.010 |
GeneticVariation |
BEFREE |
None of our patients had amyloidosis but two with E148Q/E148Q had a family history of amyloidosis and one had rapidly progressive glomerulonephritis secondary to vasculitis, which progressed to chronic renal failure.
|
15458961 |
2005 |