|
rs148636776
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
The interaction analysis showed that age and peripheral arterial disease played an interactive role in the association between HHcy and AAA, while drinking status played an interactive role in the association between MTHFR C677T polymorphism and AAA.
|
26865327 |
2016 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Peripheral arterial disease and methylenetetrahydrofolate reductase (MTHFR) C677T mutations: A case-control study and meta-analysis.
|
19157768 |
2009 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
To test whether the T variant of the C677T polymorphism in the gene for 5,10-methylenetetrahydrofolate reductase (MTHFR) would associate with three distinct forms of vascular disease, abdominal aortic aneurysm (AAA), coronary artery disease (CAD) and peripheral vascular disease (PVD).
|
15996600 |
2005 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
Methylenetetrahydrofolate reductase polymorphism 677C>T is associated with peripheral arterial disease in type 2 diabetes.
|
16274479 |
2005 |
|
rs1217691063
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We performed a MEDLINE search to identify published case-control and cohort studies correlating the factor V Leiden, prothrombin (PT) G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T (TT genotype) mutations with myocardial infarction, ischemic stroke, or peripheral vascular disease.
|
14660985 |
2003 |
|
rs7903146
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our results provide evidence that genetic variation in <i>TCF7L2</i> rs7903146 could increase risk for peripheral arterial disease in patients exhibiting long-standing type 2 diabetes.
|
31775533 |
2020 |
|
rs1994016
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic variants rs1994016 and rs3825807 in ADAMTS7 affect its mRNA expression in atherosclerotic occlusive peripheral arterial disease.
|
28205274 |
2018 |
|
rs3825807
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Genetic variants rs1994016 and rs3825807 in ADAMTS7 affect its mRNA expression in atherosclerotic occlusive peripheral arterial disease.
|
28205274 |
2018 |
|
rs1635532
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Finally, using a specific cohort of patients with PVD-associated RRD and a control population, we demonstrate a significant difference in the frequency of the COL2A1 intronic variant rs1635532 between the two groups.
|
27406592 |
2016 |
|
rs77375493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Occurrence of the JAK2 V617F mutation in patients with peripheral arterial disease.
|
25345590 |
2015 |
|
rs6668352
|
|
|
0.010 |
GeneticVariation |
BEFREE |
After adjustment for covariates, the rs6668352 A allele carriers, compared with GG homozygotes, had a higher ABI (mean ± standard error, 1.103 ± 0.006 vs. 1.084 ± 0.004, P = 0.009) and lower risk of peripheral arterial disease (PAD, defined as an ABI < 0.90, odds ratio 0.37, 95% confidence interval: 0.14-0.98, P = 0.04) in the subjects of high sodium intake.
|
23958258 |
2013 |
|
rs10757278
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Common variation at chromosome 9p21 (marked by rs10757278 or rs1333049) is associated with coronary artery disease (CAD) and peripheral vascular disease.
|
21852414 |
2011 |
|
rs12218
|
|
|
0.010 |
GeneticVariation |
BEFREE |
CC genotype of rs12218 in the SAA1 gene was associated with decreased ABI in Chinese Han subjects, which indicated that the carriers of CC genotype of rs12218 have high risk of peripheral arterial disease.
|
21449704 |
2011 |
|
rs1333049
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Common variation at chromosome 9p21 (marked by rs10757278 or rs1333049) is associated with coronary artery disease (CAD) and peripheral vascular disease.
|
21852414 |
2011 |
|
rs121909613
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The fibrinogen gamma 10034C>T polymorphism is not associated with Peripheral Arterial Disease.
|
20709368 |
2010 |
|
rs1188383936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We performed a MEDLINE search to identify published case-control and cohort studies correlating the factor V Leiden, prothrombin (PT) G20210A, and methylenetetrahydrofolate reductase (MTHFR) C677T (TT genotype) mutations with myocardial infarction, ischemic stroke, or peripheral vascular disease.
|
14660985 |
2003 |
|
rs1267969615
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biochemical parameters and the genotype and allele frequencies of three RAS gene polymorphisms, the angiotensin-converting enzyme (ACE) insertion/deletion, angiotensinogen (AGT) M235T and angiotensin II type 1 receptor (AT1R) A1166C polymorphisms were then compared between the PVD patients and 1046 age, gender and diabetes duration-matched patients without PVD.
|
14632699 |
2003 |
|
rs699
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biochemical parameters and the genotype and allele frequencies of three RAS gene polymorphisms, the angiotensin-converting enzyme (ACE) insertion/deletion, angiotensinogen (AGT) M235T and angiotensin II type 1 receptor (AT1R) A1166C polymorphisms were then compared between the PVD patients and 1046 age, gender and diabetes duration-matched patients without PVD.
|
14632699 |
2003 |
|
rs5985
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The V34L polymorphism of factor XIII and peripheral arterial disease.
|
11941274 |
2002 |
|
rs6025
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The frequency of activated protein C (APC) resistance, caused by factor V R506Q gene mutation and abnormal APC ratio, in patients with peripheral vascular diseases was analyzed.
|
9786256 |
1998 |
|
rs12713559
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A 46-yr-old woman of Celtic and Native American ancestry with primary hypercholesterolemia (total cholesterol [TC] 343 mg/dl; LDL cholesterol [LDL-C] 241 mg/dl) and pronounced peripheral vascular disease was found to be heterozygous for a novel Arg3531-->Cys mutation, caused by a C-->T transition at nucleotide 10800.
|
7883971 |
1995 |