Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1020096
rs1020096
LOC101928272
A 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs1024843
rs1024843
PTPRO
T 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs12570849
rs12570849
FRMD4A
C 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs2288493
rs2288493
TSHR ; LOC101928462
T 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs2788869
rs2788869
SYCP2L
A 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs79154414
rs79154414 		T 0.700 GeneticVariation GWASCAT The first genome-wide association study identifying new susceptibility loci for obstetric antiphospholipid syndrome. 28424481

2017
dbSNP: rs662
rs662
PON1
0.010 GeneticVariation BEFREE Association between paraoxonase-1 gene Q192R and L55M polymorphisms in systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS) in a population from Cairo of Egypt. 28185016

2017
dbSNP: rs854560
rs854560
PON1
0.010 GeneticVariation BEFREE Association between paraoxonase-1 gene Q192R and L55M polymorphisms in systemic lupus erythematosus (SLE) and anti-phospholipid syndrome (APS) in a population from Cairo of Egypt. 28185016

2017
dbSNP: rs899127658
rs899127658
F2
0.010 GeneticVariation BEFREE We examined the prevalence of prothrombotic polymorphisms (G1691A of factor V gene [FV Leiden] and G20210A of prothrombin [FII] gene), deficiencies of natural anticoagulants (protein C, protein S and antithrombin III) and antiphospholipid syndrome (APS) in patients with early ST-segment elevation MI (STEMI). 28647870

2017
dbSNP: rs10774625
rs10774625
ATXN2
0.010 GeneticVariation BEFREE Within this region, a TAC risk haplotype comprising one SNP in SH2B3 gene (rs3184504) and two SNPs in ATXN2 gene (rs10774625 and rs653178) exhibited the strongest association with thrombotic antiphospholipid syndrome (p-value = 5,9 × 10(-4) OR 95% CI 1.84 (1.32-2.55)). 23844121

2013
dbSNP: rs3184504
rs3184504
ATXN2 ; SH2B3
0.010 GeneticVariation BEFREE Within this region, a TAC risk haplotype comprising one SNP in SH2B3 gene (rs3184504) and two SNPs in ATXN2 gene (rs10774625 and rs653178) exhibited the strongest association with thrombotic antiphospholipid syndrome (p-value = 5,9 × 10(-4) OR 95% CI 1.84 (1.32-2.55)). 23844121

2013
dbSNP: rs653178
rs653178
ATXN2
0.010 GeneticVariation BEFREE Within this region, a TAC risk haplotype comprising one SNP in SH2B3 gene (rs3184504) and two SNPs in ATXN2 gene (rs10774625 and rs653178) exhibited the strongest association with thrombotic antiphospholipid syndrome (p-value = 5,9 × 10(-4) OR 95% CI 1.84 (1.32-2.55)). 23844121

2013
dbSNP: rs4581
rs4581
APOH
0.010 GeneticVariation BEFREE Val247Leu β2-glycoprotein-I allelic variant is associated with antiphospholipid syndrome: systematic review and meta-analysis. 22246055

2012
dbSNP: rs6104
rs6104
SERPINB2 ; SERPINB10
0.010 GeneticVariation BEFREE Genotype Ser413/Ser of PAI-2 polymorphism Ser413/Cys is associated with anti-phospholipid syndrome and systemic lupus erythematosus in a familial case: comparison with healthy controls. 17657675

2007
dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE Hyperhomocyteinemia and the C677T/MTHFR mutation are not common in women with antiphospholipid syndrome. 15284001

2004
dbSNP: rs121918027
rs121918027
PLG
0.010 GeneticVariation BEFREE Combined Ala601-Thr-type dysplasminogenaemia and antiphospholipid antibody syndrome in a patient with recurrent thrombosis. 12091052

2002
dbSNP: rs6025
rs6025
F5
0.010 GeneticVariation BEFREE Two young siblings who presented with an unusual recurrent severe thromboembolic phenomenon were found to have familial anti-phospholipid syndrome and were heterozygous for the factor V R506Q mutation. 8757529

1996