| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.050 | GeneticVariation | BEFREE | Polymorphism of the AGT M235T gene but not ACE I/D gene is associated with greater LVMi and relative wall thickness, indicating more concentric LVH, in Chinese peritoneal dialysis patients. | 12675870 | 2003 |
||||
|
0.050 | GeneticVariation | BEFREE | The angiotensinogen T174M and M235T and the AT1-receptor A1166C polymorphisms were related to the change in LVH during antihypertensive treatment with an AT1-receptor antagonist; of these angiotensinogen T174M was the most powerful. | 11910301 | 2002 |
||||
|
0.050 | GeneticVariation | BEFREE | These results suggest an association of combined angiotensin I-converting enzyme gene I/D polymorphism genotypes, and angiotensinogen gene M235T polymorphism genotypes with left ventricular hypertrophy due to long-term athletic training. | 11737220 | 2001 |
||||
|
0.050 | GeneticVariation | BEFREE | There are controversies concerning the association of angiotensin-converting enzyme (ACE) insertion/deletion (I/D) polymorphism with left ventricular hypertrophy (LVH), and the unclear association between angiotensinogen (ATG) M235T polymorphism and LVH. | 10646957 | 2000 |
||||
|
0.050 | GeneticVariation | BEFREE | Angiotensinogen gene M235T polymorphism is associated with the variability in left ventricular hypertrophy induced by endurance training, with athletes homozygous for the T allele having the largest hearts. | 10440164 | 1999 |
||||
|
0.010 | GeneticVariation | BEFREE | Increased ACE activity explains the significant association of rs4343 and rs4291 polymorphisms with LVH in the carriers. | 28513230 | 2017 |
||||
|
0.010 | GeneticVariation | BEFREE | Increased ACE activity explains the significant association of rs4343 and rs4291 polymorphisms with LVH in the carriers. | 28513230 | 2017 |
||||
|
0.010 | GeneticVariation | BEFREE | In a prospective follow-up study we screened 970 hypertensive patients of Caucasian descent for the Gly16Arg, Gln27Glu, and Thr164Ile beta(2)AR polymorphisms and left ventricular echocardiographic hypertrophy and assigned selected patients to enalapril or atenolol to assess left ventricular hypertrophy regression after 2-year follow-up. | 17178264 | 2006 |
||||
|
0.010 | GeneticVariation | BEFREE | In conclusion, our results suggest an association between LVH and the C825T allele of the G-protein beta3 subunit gene. | 11768721 | 2001 |