Gene: EGFR ×
Source: CURATED ×
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs121913444
rs121913444
EGFR
A 0.700 GeneticVariation CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011

2016
dbSNP: rs121913428
rs121913428
EGFR
A 0.700 GeneticVariation CLINVAR MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. 23102728

2013
dbSNP: rs121913444
rs121913444
EGFR
C 0.700 GeneticVariation CLINVAR MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. 23102728

2013
dbSNP: rs121913465
rs121913465
EGFR ; EGFR-AS1
T 0.700 GeneticVariation CLINVAR MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. 23102728

2013
dbSNP: rs397517097
rs397517097
EGFR
C 0.700 GeneticVariation CLINVAR MEK inhibitors reverse resistance in epidermal growth factor receptor mutation lung cancer cells with acquired resistance to gefitinib. 23102728

2013
dbSNP: rs121913428
rs121913428
EGFR
A 0.700 GeneticVariation CLINVAR Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer. 22753918

2012
dbSNP: rs121913444
rs121913444
EGFR
C 0.700 GeneticVariation CLINVAR Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer. 22753918

2012
dbSNP: rs121913465
rs121913465
EGFR ; EGFR-AS1
T 0.700 GeneticVariation CLINVAR Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer. 22753918

2012
dbSNP: rs397517097
rs397517097
EGFR
C 0.700 GeneticVariation CLINVAR Randomized phase II study of dacomitinib (PF-00299804), an irreversible pan-human epidermal growth factor receptor inhibitor, versus erlotinib in patients with advanced non-small-cell lung cancer. 22753918

2012
dbSNP: rs150036236
rs150036236
EGFR
A 0.700 CausalMutation CLINVAR Clinical implications of novel activating EGFR mutations in malignant peritoneal mesothelioma. 20942962

2010