| Variant | Gene | Risk Allele | Score vda | Association Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||
|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | BEFREE | Association study of methylenetetrahydrofolate reductase C677T mutation with cerebral venous thrombosis in an Iranian population. | 26083986 | 2015 |
||||
|
0.070 | GeneticVariation | BEFREE | Recurrent cerebral venous thrombosis associated with heterozygote methylenetetrahydrofolate reductase C677T mutation and sickle cell trait without homocysteinemia: an autopsy case report and review of literature. | 25074331 | 2014 |
||||
|
0.070 | GeneticVariation | BEFREE | Thrombophilic polymorphisms - factor V Leiden G1691A, prothrombin G20210A and MTHFR C677T - in Tunisian patients with cerebral venous thrombosis. | 22721898 | 2012 |
||||
|
0.070 | GeneticVariation | BEFREE | The authors describe the case of a 12-year-old male with acute lymphoblastic leukemia and a homozygous methylenetetrahydrofolate reductase C677T mutation, who developed subacute methotrexate-induced toxicity and cerebral venous thrombosis after receiving intrathecal methotrexate. | 20121554 | 2010 |
||||
|
0.070 | GeneticVariation | BEFREE | We report a case of cerebral venous thrombosis (CVT) due to tyrotoxicosis in a patient with methylenetetrahydro-folate-reductase (MTHFR) gene polymorphism C677T, (genotype 677TT), in which discontinuation of intravenous heparin was followed by clinical and radiological worsening despite warfarin treatment. | 18941937 | 2008 |
||||
|
0.070 | GeneticVariation | BEFREE | The aim of this study was to evaluate the significance of factor V (FV) G1691A, prothrombin G20210A, methylenetetrahydrofolate reductase (MTHFR) C677T, and plasminogen activator inhibitor-1 (PAI-1) 4G/5G genotypes in development of childhood cerebral thrombosis (CT). | 17456624 | 2007 |
||||
|
0.070 | GeneticVariation | BEFREE | We report three patients with cerebral vein thrombosis (CVT) in which the only risk factor we were able to identify was increased blood homocysteine levels and the C677T polymorphism in both alleles of the methylene tetrahydrofolate reductase MTHFR gene. | 12522678 | 2002 |
||||
|
0.010 | GeneticVariation | BEFREE | Role of methylenetetrahydrofolate reductase A1298C polymorphism in cerebral venous thrombosis. | 23314385 | 2013 |