Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs995030
rs995030
0.710 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs995030
rs995030
0.710 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs995030
rs995030
0.710 GeneticVariation BEFREE The SNP rs995030 was strongly associated with risk of testicular cancer (per allele OR: 1.83; 95%CI: 1.26-2.64), but it did not modify the association between number of children and the risk of testicular cancer. 28036409

2016

dbSNP: rs11104952
rs11104952
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs11104952
rs11104952
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs1352947
rs1352947
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs1352947
rs1352947
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs1472899
rs1472899
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs1472899
rs1472899
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs2524594
rs2524594
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs3770112
rs3770112
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs3782179
rs3782179
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs3782179
rs3782179
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs3782181
rs3782181
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs3782181
rs3782181
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs4474514
rs4474514
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs6490478
rs6490478
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs6534637
rs6534637
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs7486184
rs7486184
0.700 GeneticVariation GWASDB Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer. 19483682

2009

dbSNP: rs7486184
rs7486184
0.700 GeneticVariation GWASDB A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility. 21551455

2011

dbSNP: rs1048943
rs1048943
0.010 GeneticVariation BEFREE Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit. 31107374

2019

dbSNP: rs1695
rs1695
0.010 GeneticVariation BEFREE The results of the multivariate analysis showed that the presence of variant alleles of GSTP1 (rs1695) together with a smoking habit and a family history of cancer accounted for a 15.9% risk of developing TCa in the Chilean population. 31107374

2019

dbSNP: rs1799889
rs1799889
0.010 GeneticVariation BEFREE The authors investigated whether the germline 4G/5G deletion/insertion polymorphism in the PAI-1 promoter (rs1799889), which may influence PAI-1 expression, is associated with survival and chemotherapy-related vascular toxicity in testicular cancer (TC). 20737565

2010

dbSNP: rs1799945
rs1799945
0.010 GeneticVariation BEFREE Overall survival, testicular cancer-related survival, and change in renal function were not associated with the H63D variant. 27033261

2016

dbSNP: rs1872328
rs1872328
0.010 GeneticVariation BEFREE <i>WFS1</i> rs62283056 was not significantly associated with ototoxicity caused by cisplatin (<i>P</i> = 0.39); however, this variant was associated with hearing loss attributable to any cause [<i>P</i> = 5.67 × 10<sup>-3</sup>, OR (95% CI): 3.2 (1.4-7.7)].<b>Conclusions:</b> This study has provided the first evidence for the role of <i>ACYP2</i> rs1872328 in cisplatin-induced ototoxicity in patients with testicular cancer. 29358504

2018