rs1048943
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Variant alleles found to increase the risk of developing TCa were CYP1A1*2C (rs1048943), GSTP1 (rs1695), and GSTT1null, especially when in conjunction with a cancer family history and/or a smoking habit.
|
31107374 |
2019 |
rs11104952
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs11104952
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.
|
21551455 |
2011 |
rs121913105
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs121913482
|
|
T |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs121913483
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs121913506
|
|
C |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1352947
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs1352947
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.
|
21551455 |
2011 |
rs137853078
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs1472899
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.
|
21551455 |
2011 |
rs1472899
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs1695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The results of the multivariate analysis showed that the presence of variant alleles of GSTP1 (rs1695) together with a smoking habit and a family history of cancer accounted for a 15.9% risk of developing TCa in the Chilean population.
|
31107374 |
2019 |
rs1799889
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The authors investigated whether the germline 4G/5G deletion/insertion polymorphism in the PAI-1 promoter (rs1799889), which may influence PAI-1 expression, is associated with survival and chemotherapy-related vascular toxicity in testicular cancer (TC).
|
20737565 |
2010 |
rs1799945
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Overall survival, testicular cancer-related survival, and change in renal function were not associated with the H63D variant.
|
27033261 |
2016 |
rs1872328
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>WFS1</i> rs62283056 was not significantly associated with ototoxicity caused by cisplatin (<i>P</i> = 0.39); however, this variant was associated with hearing loss attributable to any cause [<i>P</i> = 5.67 × 10<sup>-3</sup>, OR (95% CI): 3.2 (1.4-7.7)].<b>Conclusions:</b> This study has provided the first evidence for the role of <i>ACYP2</i> rs1872328 in cisplatin-induced ototoxicity in patients with testicular cancer.
|
29358504 |
2018 |
rs2293275
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A statistical significant difference was observed in patients being heterozygous for the LHR Asn312Ser polymorphism when comparing genotypes between all TC cases and controls (OR = 0.66, 95% CI = 0.48-0.89, p(adj) = 0.049).
|
22882535 |
2012 |
rs2524594
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs28931614
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs28933068
|
|
G |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs370432633
|
|
A |
0.700 |
CausalMutation |
CLINVAR |
|
|
|
rs3770112
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs3782179
|
|
|
0.700 |
GeneticVariation |
GWASDB |
A second independent locus within DMRT1 is associated with testicular germ cell tumor susceptibility.
|
21551455 |
2011 |
rs3782179
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |
rs3782181
|
|
|
0.700 |
GeneticVariation |
GWASDB |
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer.
|
19483682 |
2009 |