Compared with the CTCTAA/CTCTAA genotype, the GC/GC and GC/CTCTAA genotypes of rs17860508 could significantly increase the risk of ovarian endometriosis development (OR = 1.58, 95% CI = 1.19-2.09; OR = 1.37, 95% CI = 1.08-1.74, respectively).
The study suggests that the endometriosis-associated genetic polymorphisms (rs12700667) from GWAS be associated with the risk of developing ovarian endometriosis in North Chinese women.