|
rs1463038513
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Prevalence of adenomatous polyps in the pathology specimens of the study participants, stratified by their APC I1307K polymorphism status, was studied in 900 consecutive cases of colorectal cancer diagnosed in northern Israel between 1998 and 2002, within the framework of a population-based, case-controlled study (MECC Study).
|
16228836 |
2005 |
|
rs1801155
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Prevalence of adenomatous polyps in the pathology specimens of the study participants, stratified by their APC I1307K polymorphism status, was studied in 900 consecutive cases of colorectal cancer diagnosed in northern Israel between 1998 and 2002, within the framework of a population-based, case-controlled study (MECC Study).
|
16228836 |
2005 |
|
rs1463038513
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The high frequency of I1307K colorectal cancer patients found in the Ashkenazi Jewish community of Ottawa and the equivalent proportion of carriers and noncarriers who developed adenomatous polyps suggest that in this community, I1307K is associated with a significant predisposition to carcinoma but not adenoma.
|
11159880 |
2001 |
|
rs1463038513
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among the genetic defects associated with CRC, the APC I1307K mutation has been detected nearly exclusively in individuals of Ashkenazi Jewish (AJ) origin, occurring in 6%-7% of the AJ general population and in 10%-28% of AJ with a either a personal or family history of CRC or adenomatous polyps.
|
11354631 |
2001 |
|
rs1801155
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The high frequency of I1307K colorectal cancer patients found in the Ashkenazi Jewish community of Ottawa and the equivalent proportion of carriers and noncarriers who developed adenomatous polyps suggest that in this community, I1307K is associated with a significant predisposition to carcinoma but not adenoma.
|
11159880 |
2001 |
|
rs1801155
|
|
|
0.040 |
GeneticVariation |
BEFREE |
Among the genetic defects associated with CRC, the APC I1307K mutation has been detected nearly exclusively in individuals of Ashkenazi Jewish (AJ) origin, occurring in 6%-7% of the AJ general population and in 10%-28% of AJ with a either a personal or family history of CRC or adenomatous polyps.
|
11354631 |
2001 |
|
rs1463038513
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps.
|
10938175 |
2000 |
|
rs1801155
|
|
|
0.040 |
GeneticVariation |
BEFREE |
The frequency of the APC I1307K mutation is elevated in Ashkenazi Jewish patients with adenomatous polyps, but not hyperplastic polyps.
|
10938175 |
2000 |
|
rs1801166
|
|
|
0.020 |
GeneticVariation |
BEFREE |
The APC E1317Q variant in adenomatous polyps and colorectal cancers.
|
14578138 |
2003 |
|
rs1801166
|
|
|
0.020 |
GeneticVariation |
BEFREE |
In all, E1317Q was identified in two of 182 patients with adenomatous polyps (1.1%) and in two of 235 controls (0.8%) (p = 0.59).
|
12537656 |
2002 |
|
rs776197565
|
|
|
0.010 |
GeneticVariation |
BEFREE |
The Q324H variant was negatively associated with the number of adenomatous polyps (OR -5.23).
|
25822476 |
2015 |
|
rs587782868
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biallelic mutations for Y165C and/or G382D were not found in any of those undergoing screening colonoscopy with 0-3 polyps (n = 400), in those APC-negative patients with <20 adenomatous polyps (n = 26), or in those with CRC who were older than 50 years (n = 328).
|
15236166 |
2004 |
|
rs770649674
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Biallelic mutations for Y165C and/or G382D were not found in any of those undergoing screening colonoscopy with 0-3 polyps (n = 400), in those APC-negative patients with <20 adenomatous polyps (n = 26), or in those with CRC who were older than 50 years (n = 328).
|
15236166 |
2004 |