Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs104894396
rs104894396
GJB2
T 0.700 CausalMutation CLINVAR

dbSNP: rs1163944538
rs1163944538
TMEM94
GA 0.700 CausalMutation CLINVAR

dbSNP: rs1352010373
rs1352010373
TMEM94
C 0.700 CausalMutation CLINVAR

dbSNP: rs148881970
rs148881970
NAGLU
G 0.700 CausalMutation CLINVAR

dbSNP: rs1554317002
rs1554317002
CDK13 ; LOC112267983
T 0.700 GeneticVariation CLINVAR

dbSNP: rs1555735545
rs1555735545
STRN4 ; FKRP
A 0.700 CausalMutation CLINVAR

dbSNP: rs28937900
rs28937900
FKRP
A 0.700 CausalMutation CLINVAR

dbSNP: rs370717845
rs370717845
HGSNAT
A 0.700 CausalMutation CLINVAR

dbSNP: rs555145190
rs555145190
NAGLU
T 0.700 CausalMutation CLINVAR

dbSNP: rs63751011
rs63751011
MAPT
T 0.700 CausalMutation CLINVAR

dbSNP: rs768823392
rs768823392
SPG7
A 0.700 CausalMutation CLINVAR

dbSNP: rs80356702
rs80356702
CLCN1
A 0.700 GeneticVariation CLINVAR

dbSNP: rs104893877
rs104893877
SNCA
0.020 GeneticVariation BEFREE A53T mice also exhibit spatial memory deficits at 6 and 12 months, as demonstrated by Y-maze performance. 23936403

2013
dbSNP: rs1424266770
rs1424266770
CASP3
0.010 GeneticVariation BEFREE H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment. 24439478

2014
dbSNP: rs1799945
rs1799945
HFE ; LOC108783645
0.010 GeneticVariation BEFREE H63D mutation in hemochromatosis alters cholesterol metabolism and induces memory impairment. 24439478

2014
dbSNP: rs63750424
rs63750424
MAPT
0.020 GeneticVariation BEFREE R406W patients often show a long course of disease with marked memory deficits. 29370822

2018
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE A Val(66)Met single-nucleotide polymorphism (SNP) in the brain-derived neurotrophic factor (BDNF) gene impairs activity-dependent BDNF release in cultured hippocampal neurons and predicts impaired memory and exaggerated basal hippocampal activity in healthy humans. 23319002

2013
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE A Val(66)Met single-nucleotide polymorphism (SNP) in the brain-derived neurotrophic factor (BDNF) gene impairs activity-dependent BDNF release in cultured hippocampal neurons and predicts impaired memory and exaggerated basal hippocampal activity in healthy humans. 23319002

2013
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE A previously reported valine to methionine substitution at amino-acid position 66 (BDNF Val66Met) seems to account for memory disturbance and hippocampal dysfunction. 17392738

2007
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE A previously reported valine to methionine substitution at amino-acid position 66 (BDNF Val66Met) seems to account for memory disturbance and hippocampal dysfunction. 17392738

2007
dbSNP: rs572842823
rs572842823
APP
0.010 GeneticVariation BEFREE A recently described mouse line, Tg(HuAPP695.K670N/M671L)2576, expressing human amyloid precursor protein with a familial AD gene mutation, age-related amyloid deposits, and memory deficits, was found to develop a significant microglial response using Griffonia simplicifolia lectin or phosphotyrosine probe to identify microglia Both Griffonia simplicifolia lectin and phosphotyrosine staining showed increased numbers of intensely labeled, often enlarged microglia clustered in and around plaques, consistent with microglial activation related to beta-amyloid formation. 9422548

1998
dbSNP: rs17125721
rs17125721
PSEN1
0.010 GeneticVariation BEFREE Association between the presenilin-1 mutation Glu318Gly and complaints of memory impairment. 11755019

2002
dbSNP: rs281865071
rs281865071
CHRNB2
0.020 GeneticVariation BEFREE Autosomal dominant nocturnal frontal lobe epilepsy and mild memory impairment associated with CHRNB2 mutation I312M in the neuronal nicotinic acetylcholine receptor. 18534914

2008
dbSNP: rs6265
rs6265
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. 27521573

2016
dbSNP: rs759834365
rs759834365
BDNF ; BDNF-AS
0.030 GeneticVariation BEFREE BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease. 27521573

2016