Gene: SDHB ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Relevance of germline mutation screening in both familial and sporadic head and neck paraganglioma for early diagnosis and clinical management. 20208144

2010
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma. 25873086

2015
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Role of rapid sequence whole-body MRI screening in SDH-associated hereditary paraganglioma families. 23934599

2014
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR The succinate dehydrogenase genetic testing in a large prospective series of patients with paragangliomas. 19454582

2009
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Germline SDHB mutations are common in patients with apparently sporadic sympathetic paragangliomas. 18382370

2008
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Clinical predictors for germline mutations in head and neck paraganglioma patients: cost reduction strategy in genetic diagnostic process as fall-out. 19351833

2009
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Mutations in the SDHB gene are associated with extra-adrenal and/or malignant phaeochromocytomas. 14500403

2003
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function. 22835832

2012
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Screening of mutations in genes that predispose to hereditary paragangliomas and pheochromocytomas. 22517554

2012
dbSNP: rs1553176976
rs1553176976
SDHB
ATAGC 0.700 GeneticVariation CLINVAR

dbSNP: rs1553176979
rs1553176979
SDHB
AC 0.700 GeneticVariation CLINVAR

dbSNP: rs1553177436
rs1553177436
SDHB
T 0.700 CausalMutation CLINVAR

dbSNP: rs1553177676
rs1553177676
SDHB
A 0.700 CausalMutation CLINVAR

dbSNP: rs1553177678
rs1553177678
SDHB
C 0.700 CausalMutation CLINVAR Inherited mutations in pheochromocytoma and paraganglioma: why all patients should be offered genetic testing. 23512077

2013
dbSNP: rs1553178726
rs1553178726
SDHB
G 0.700 CausalMutation CLINVAR

dbSNP: rs1557738304
rs1557738304
SDHB
TC 0.700 GeneticVariation CLINVAR

dbSNP: rs1557739966
rs1557739966
SDHB
G 0.700 GeneticVariation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs1557739966
rs1557739966
SDHB
G 0.700 GeneticVariation CLINVAR How general practitioners manage depressive illness: developing a method of audit. 7143317

1982
dbSNP: rs1557741425
rs1557741425
SDHB
AC 0.700 CausalMutation CLINVAR

dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Familial paragangliomas: case report and literature review. 18753105

2009
dbSNP: rs200245469
rs200245469
SDHB
A 0.700 GeneticVariation CLINVAR Tumor risks and genotype-phenotype-proteotype analysis in 358 patients with germline mutations in SDHB and SDHD. 19802898

2010
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency. 22972948

2012
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Magnetic resonance imaging spectrum of succinate dehydrogenase-related infantile leukoencephalopathy. 26642834

2016
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling. 27604842

2017
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Mitochondrial leukoencephalopathy and complex II deficiency associated with a recessive SDHB mutation with reduced penetrance. 26925370

2015