Gene: SDHB ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Tumour risks and genotype-phenotype correlations associated with germline variants in succinate dehydrogenase subunit genes SDHB, SDHC and SDHD. 29386252

2018
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Leukoencephalopathy due to Complex II Deficiency and Bi-Allelic SDHB Mutations: Further Cases and Implications for Genetic Counselling. 27604842

2017
dbSNP: rs74315370
rs74315370
SDHB
C 0.700 CausalMutation CLINVAR Analysis of SDHAF3 in familial and sporadic pheochromocytoma and paraganglioma. 28738844

2017
dbSNP: rs751000085
rs751000085
SDHB
A 0.700 CausalMutation CLINVAR The phenotype of SDHB germline mutation carriers: a nationwide study. 28490599

2017
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies. 28349240

2017
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR SDHB-related pheochromocytoma and paraganglioma penetrance and genotype-phenotype correlations. 28374168

2017
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Magnetic resonance imaging spectrum of succinate dehydrogenase-related infantile leukoencephalopathy. 26642834

2016
dbSNP: rs397516833
rs397516833
SDHB
G 0.700 CausalMutation CLINVAR Cardiac Paraganglioma Arising From the Right Atrioventricular Groove in a Paraganglioma-Pheochromocytoma Family Syndrome With Evidence of SDHB Gene Mutation: An Unusual Presentation. 27549546

2016
dbSNP: rs587782604
rs587782604
SDHB
T 0.700 CausalMutation CLINVAR Germline mutations and genotype-phenotype correlation in Asian Indian patients with pheochromocytoma and paraganglioma. 27539324

2016
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 CausalMutation CLINVAR Germline mutations and genotype-phenotype correlation in Asian Indian patients with pheochromocytoma and paraganglioma. 27539324

2016
dbSNP: rs772551056
rs772551056
SDHB
T 0.700 CausalMutation CLINVAR SDHB-Deficient Cancers: The Role of Mutations That Impair Iron Sulfur Cluster Delivery. 26719882

2016
dbSNP: rs786201063
rs786201063
SDHB
T 0.700 CausalMutation CLINVAR Germline mutations and genotype-phenotype correlation in Asian Indian patients with pheochromocytoma and paraganglioma. 27539324

2016
dbSNP: rs786201095
rs786201095
SDHB
C 0.700 CausalMutation CLINVAR Carney triad can be (rarely) associated with germline succinate dehydrogenase defects. 26173966

2016
dbSNP: rs138996609
rs138996609
SDHB
A 0.700 CausalMutation CLINVAR Superiority of [68Ga]-DOTATATE PET/CT to Other Functional Imaging Modalities in the Localization of SDHB-Associated Metastatic Pheochromocytoma and Paraganglioma. 25873086

2015
dbSNP: rs1557739966
rs1557739966
SDHB
G 0.700 GeneticVariation CLINVAR 15 YEARS OF PARAGANGLIOMA: Clinical manifestations of paraganglioma syndromes types 1-5. 26273102

2015
dbSNP: rs202101384
rs202101384
SDHB
A 0.700 GeneticVariation CLINVAR Mitochondrial leukoencephalopathy and complex II deficiency associated with a recessive SDHB mutation with reduced penetrance. 26925370

2015
dbSNP: rs267607032
rs267607032
SDHB
A 0.700 CausalMutation CLINVAR Paraganglioma Presenting as Postpartum Fever of Unknown Origin. 26236513

2015
dbSNP: rs398123690
rs398123690
SDHB
C 0.700 CausalMutation CLINVAR Genetics of Apparently Sporadic Pheochromocytoma and Paraganglioma in a Chinese Population. 26267327

2015
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 CausalMutation CLINVAR SDHD immunohistochemistry: a new tool to validate SDHx mutations in pheochromocytoma/paraganglioma. 25405498

2015
dbSNP: rs587782604
rs587782604
SDHB
T 0.700 CausalMutation CLINVAR Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice. 25695889

2015
dbSNP: rs587782604
rs587782604
SDHB
A 0.700 CausalMutation CLINVAR Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum. 26259135

2015
dbSNP: rs587782604
rs587782604
SDHB
T 0.700 CausalMutation CLINVAR Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum. 26259135

2015
dbSNP: rs587782604
rs587782604
SDHB
T 0.700 CausalMutation CLINVAR [Intrapericardical paraganglioma associated with mutation in succinate dehydrogenase enzyme gene]. 24939699

2015
dbSNP: rs74315368
rs74315368
SDHB
T 0.700 CausalMutation CLINVAR Structural and functional consequences of succinate dehydrogenase subunit B mutations. 25972245

2015
dbSNP: rs74315368
rs74315368
SDHB
T 0.700 CausalMutation CLINVAR Additive effect of nuclear and mitochondrial mutations in a patient with mitochondrial encephalomyopathy. 25736212

2015