rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E mutation in papillary thyroid cancer is correlated with adverse clinicopathological features but not with iodine exposure.
|
31135058 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Evaluation of BRAF V600E mutation status combined with cytomorphological features for diagnosis of PTC in cytologically indeterminate thyroid nodules can significantly improve diagnostic accuracy and reduce the number of diagnostic operations (calculator available at www.ptc-calc.we2host.lt).
|
29566402 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
PTC with BRAF V600E mutation showed higher expression of ATX, LPA1, LPA2, and LPA3 than PTC without BRAF V600E mutation (p < 0.001).
|
31455351 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Seven of the 9 indeterminate and suspicious cases with the BRAF V600E mutation had surgical follow-up, and they were all confirmed to be PTC.
|
30620446 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The most common genetic alteration identified in papillary thyroid cancer (PTC) encodes a valine to glutamic acid change at position 600 (V600E) in the BRAF proto-oncoprotein.
|
30988823 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The BRAF V600E mutation was identified in 15/83 of PTCs and significantly correlated with higher age of patients and classical variant of PTC.
|
31085772 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We analyzed mutations of BRAF (V600E) and TERT promoter (C228T, C250T) in tumor DNA from 141 patients (75 with classical variant PTC, CVPTC; 66 with follicular variant PTC, FVPTC) recruited through a multi-center study.
|
31454788 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Associations of the BRAF V600E Mutation and PAQR3 Protein Expression with Papillary Thyroid Carcinoma Clinicopathological Features.
|
31758408 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We conclude that coexisting BRAF V600E and TERT mutations in patients with PTC are associated with poor initial prognostic factors and clinical course and may be useful for predicting a worse response to therapy, recurrence, and poorer outcome than in patients without the above mutations.
|
31305897 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
TERT or NRAS mutation was likely to coexist with BRAF V600E mutation in PTC.
|
31300059 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E mutations occur in approximately 40% of all patients with papillary thyroid cancer (PTC) and are associated with a worse prognosis in population studies.
|
31085763 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Detection of BRAF V600E mutation in fine-needle aspiration fluid of papillary thyroid carcinoma by droplet digital PCR.
|
30682328 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The immunocytochemical expression of VE-1 (BRAF V600E-related) antibody identifies the aggressive variants of papillary thyroid carcinoma on liquid-based cytology.
|
30875124 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
In the Cancer Genome Atlas (TCGA) PTC cohort, higher ENS-653 expression was correlated with more frequent BRAF (V600E) mutation and poorer disease-free survival.
|
30940124 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E mutation papillary thyroid cancer (PTC) is more aggressive with a higher risk of lymph node involvement and a poorer prognosis.
|
30688735 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
38.2% of human PTCs displayed high expression of AXL that positively correlated with RAI-refractoriness and disease persistence or recurrence, especially when combined with v-raf murine sarcoma viral oncogene homolog B(BRAF) V600E mutation.
|
31181609 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E and Retinoic Acid in Radioiodine-Refractory Papillary Thyroid Cancer.
|
30396219 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
We further discuss a case with a single BRAF V600E cytological mutant lacking a postoperative PTC diagnosis and discuss the limitations of BRAF V600E detection using puncture elution fluid.
|
31529211 |
2019 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
IHC is a suitable method to screen BRAF V600E mutation in FFPE samples of CRCs and PTCs.
|
30009773 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E Mutation-Assisted Risk Stratification of Solitary Intrathyroidal Papillary Thyroid Cancer for Precision Treatment.
|
29165667 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
BRAF V600E Gene Mutation Is Associated With Bilateral Malignancy of Papillary Thyroid Cancer.
|
30219154 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
These results suggest that ZNF703 may be of potential use as a new marker for PTC prognosis and therapy that functions independent of BRAF V600E expression.
|
30361900 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
The BRAF T1799A mutation was detected in 10 PTC cases, while two different NRAS mutations in codon 61 (C181A and A182G) were found in 2 PTC cases.
|
30361901 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
Conclusion The long-observed age-associated mortality risk in PTC is dependent on BRAF status; age is a strong, continuous, and independent mortality risk factor in patients with BRAF V600E mutation but not in patients with wild-type BRAF.
|
29240540 |
2018 |
rs113488022
|
|
|
0.800 |
GeneticVariation |
BEFREE |
<i>BRAF</i>V600E (c.1799T>A) somatic mutation evaluation in fine needle aspiration biopsies (FNAB) is a powerful diagnostic tool in the settings of papillary thyroid cancer (PTC).
|
30374428 |
2018 |