|
rs121913530
|
|
|
0.770 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs121913316
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs142771326
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1446876735
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs1805076
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs5030807
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs973682124
|
|
|
0.700 |
GeneticVariation |
UNIPROT |
|
|
|
|
rs4787050
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> The present study revealed that rs4787050 and rs8045980 in <i>RBFOX1</i> may be meaningful as a novel biomarker for lung cancer susceptibility.
|
31512508 |
2019 |
|
rs8045980
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<b>Conclusion:</b> The present study revealed that rs4787050 and rs8045980 in <i>RBFOX1</i> may be meaningful as a novel biomarker for lung cancer susceptibility.
|
31512508 |
2019 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<b>Purpose:</b> Acquired <i>EGFR</i> T790M mutations are the most frequently identified resistance mechanism to EGFR tyrosine kinase inhibitors (TKI) in patients with <i>EGFR</i>-mutant lung cancers.
|
28954786 |
2017 |
|
rs10053847
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>IL-7R</i> rs10053847 was correlated with a decreased LC risk, while <i>IL-7R</i> rs10213865 was correlated with an elevated lung adenocarcinoma risk, implying these two SNPs might play essential roles in LC risk evaluation.
|
31354347 |
2019 |
|
rs10213865
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>IL-7R</i> rs10053847 was correlated with a decreased LC risk, while <i>IL-7R</i> rs10213865 was correlated with an elevated lung adenocarcinoma risk, implying these two SNPs might play essential roles in LC risk evaluation.
|
31354347 |
2019 |
|
rs1800566
|
|
|
0.040 |
GeneticVariation |
BEFREE |
<i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer.
|
28529598 |
2017 |
|
rs4673
|
|
|
0.010 |
GeneticVariation |
BEFREE |
<i>NQO1</i> rs1800566 was significantly associated with lung cancer risk and smoking may influence the association between <i>CYBA</i> rs4673 and the risk of lung cancer.
|
28529598 |
2017 |
|
rs4646903
|
|
|
0.040 |
GeneticVariation |
BEFREE |
1.The CYP1A1 T6235C polymorphism (rs4646903) gene polymorphism has been linked to the development of coronary heart disease and cigarette smoking-related lung cancer.
|
19650794 |
2010 |
|
rs7354
|
|
|
0.010 |
GeneticVariation |
BEFREE |
19p13.3-GADD45B rs7354 was associated with lung cancer risk among ≤20 (years) smokers [C/A-A/A versus CC, OR (95% CI) = 3.20 (1.11-9.20), P = 0.025] in a dominant model stratified by smoking duration.
|
28870783 |
2017 |
|
rs2352028
|
|
|
0.030 |
GeneticVariation |
BEFREE |
44 top candidate SNPs were identified that might alter the risk of lung cancer in never smokers. rs2352028 at chromosome 13q31.3 was subsequently replicated with an additive genetic model in the four independent studies, with a combined odds ratio of 1.46 (95% CI 1.26-1.70, p=5.94x10(-6)).
|
20304703 |
2010 |
|
rs1465952
|
|
|
0.010 |
GeneticVariation |
BEFREE |
68 SNPs were significantly associated with lung cancer in the discovery set and tested for replication.Among the 68 SNPs, three SNPs (corepressor interacting with RBPJ 1 (CIR1) rs13009079T>C, ribonucleotide reductase M1 (RRM1) rs1465952T>C and solute carrier family 38, member 4 (SLC38A4) rs2429467C>T) consistantly showed significant associations with lung cancer in the replication study.
|
27587543 |
2016 |
|
rs2429467
|
|
|
0.010 |
GeneticVariation |
BEFREE |
68 SNPs were significantly associated with lung cancer in the discovery set and tested for replication.Among the 68 SNPs, three SNPs (corepressor interacting with RBPJ 1 (CIR1) rs13009079T>C, ribonucleotide reductase M1 (RRM1) rs1465952T>C and solute carrier family 38, member 4 (SLC38A4) rs2429467C>T) consistantly showed significant associations with lung cancer in the replication study.
|
27587543 |
2016 |
|
rs2241880
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lung cancer cell lines stably transfected with ATG16L1: rs2241880 (T300A) were established.
|
28441070 |
2017 |
|
rs751688663
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lung cancer cell lines stably transfected with ATG16L1: rs2241880 (T300A) were established.
|
28441070 |
2017 |
|
rs763375936
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lung cancer cell lines stably transfected with ATG16L1: rs2241880 (T300A) were established.
|
28441070 |
2017 |
|
rs772776695
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Lung cancer cell lines stably transfected with ATG16L1: rs2241880 (T300A) were established.
|
28441070 |
2017 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Lung cancer harboring epidermal growth factor receptor (EGFR) mutations and treated with EGFR tyrosine kinase inhibitors (TKIs) all eventually develop acquired resistance to the treatment, with half of the patients developing EGFR T790M resistance mutations.
|
28620690 |
2017 |
|
rs876658657
|
|
|
0.030 |
GeneticVariation |
BEFREE |
-93G-->A polymorphism of hMLH1 and risk of primary lung cancer.
|
15382050 |
2004 |