|
rs113488022
|
|
|
0.100 |
GeneticVariation |
BEFREE |
V599E BRAF mutation was uncommon in Japanese lung cancer.
|
16376942 |
2006 |
|
rs121913377
|
|
|
0.100 |
GeneticVariation |
BEFREE |
V599E BRAF mutation was uncommon in Japanese lung cancer.
|
16376942 |
2006 |
|
rs397517132
|
|
|
0.060 |
GeneticVariation |
BEFREE |
V599E BRAF mutation was uncommon in Japanese lung cancer.
|
16376942 |
2006 |
|
rs140693
|
|
|
0.030 |
GeneticVariation |
BEFREE |
Glu346Lys polymorphism in the methyl-CpG binding domain 4 gene and the risk of primary lung cancer.
|
16803845 |
2006 |
|
rs1057519847
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The EGFR mutation status, especially L858R mutation might be correlated with the clinico-pathological features related to good response to gefitinib, such as gender, smoking history, and pathological subtypes of Japanese lung cancers.
|
16890322 |
2006 |
|
rs1057519848
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The EGFR mutation status, especially L858R mutation might be correlated with the clinico-pathological features related to good response to gefitinib, such as gender, smoking history, and pathological subtypes of Japanese lung cancers.
|
16890322 |
2006 |
|
rs121434568
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The EGFR mutation status, especially L858R mutation might be correlated with the clinico-pathological features related to good response to gefitinib, such as gender, smoking history, and pathological subtypes of Japanese lung cancers.
|
16890322 |
2006 |
|
rs25487
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Arg399Gln is a SNP with some functional evidence and has been shown previously to be an important SNP associated with lung cancer, mostly for Asians.
|
19029194 |
2009 |
|
rs369410616
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Arg399Gln is a SNP with some functional evidence and has been shown previously to be an important SNP associated with lung cancer, mostly for Asians.
|
19029194 |
2009 |
|
rs727504256
|
|
|
0.010 |
GeneticVariation |
BEFREE |
E709K and Ins770G as well as L858R appear to be functional mutations based on the use of Ba/F3 cells.
|
19726454 |
2009 |
|
rs1130409
|
|
|
0.100 |
GeneticVariation |
BEFREE |
rs1130409 of APEX1 can be a predictor of RP grades ≥3 among patients with lung cancer.
|
24884729 |
2014 |
|
rs146795390
|
|
|
0.030 |
GeneticVariation |
BEFREE |
V843I, a lung cancer predisposing EGFR mutation, is responsible for resistance to EGFR tyrosine kinase inhibitors.
|
25057940 |
2014 |
|
rs833061
|
|
|
0.030 |
GeneticVariation |
BEFREE |
rs833061 and rs699947 on promoter gene of vascular endothelial growth factor (VEGF) and associated lung cancer susceptibility and survival: a meta-analysis.
|
25468805 |
2014 |
|
rs12901682
|
|
|
0.010 |
GeneticVariation |
BEFREE |
rs12901682 is associated with lung cancer risks (OR = 1.45, 95 % CI, 1.04-2.02; P = 0.029).
|
25744645 |
2015 |
|
rs121913465
|
|
|
0.010 |
GeneticVariation |
BEFREE |
S768I Mutation in EGFR in Patients with Lung Cancer.
|
27211795 |
2016 |
|
rs397517108
|
|
|
0.010 |
GeneticVariation |
BEFREE |
S768I Mutation in EGFR in Patients with Lung Cancer.
|
27211795 |
2016 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
T790M mutant copy number quantified via ddPCR predicts outcome after osimertinib treatment in lung cancer.
|
29963252 |
2018 |
|
rs121913444
|
|
|
0.010 |
GeneticVariation |
BEFREE |
L861Q may be a clinically valuable mutation because it is known to sensitize non-small-cell lung cancers to treatment with the second-generation EGFR TKI afatinib in particular.
|
30305059 |
2018 |
|
rs121434569
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A 79-year-old woman had disease progression during third-line treatment with osimertinib for an EGFR L858R/T790M-mutant lung cancer.
|
31254668 |
2019 |
|
rs3743078
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A case-control study of 529 cases and 567 controls was performed to study the association of three SNPs (rs3743076, rs3743078, and rs3743073) in CHRNA3 with lung cancer risk in Chinese Han population using logistic regression models.
|
20234319 |
2010 |
|
rs1130409
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A common APE1 polymorphism, a T-->G transversion (Asp 148 Glu), was previously shown to be associated with risk of lung cancer, an association that was modified by cigarette smoking.
|
16425270 |
2006 |
|
rs1051740
|
|
|
0.080 |
GeneticVariation |
BEFREE |
A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer.
|
21445251 |
2011 |
|
rs2234922
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A comprehensive systematic review and meta-analysis was performed of available studies on these two polymorphisms and cancer risk published up to November 2010, consisting of 84 studies (31144 cases and 42439 controls) for Tyr113His and 77 studies (28496 cases and 38506 controls) for His139Arg primarily focused on lung cancer, upper aerodigestive tract (UADT) cancers (including oral, pharynx, larynx and esophagus cancers), colorectal cancer or adenoma, bladder cancer and breast cancer.
|
21445251 |
2011 |
|
rs146795390
|
|
|
0.030 |
GeneticVariation |
BEFREE |
A dramatic lung cancer course in a patient with a rare EGFR germline mutation exon 21 V843I: Is EGFR TKI resistance predictable?
|
23380224 |
2013 |
|
rs11637635
|
|
|
0.010 |
GeneticVariation |
BEFREE |
A four-SNP haplotype spanning CHRNA5 (rs11637635 C, rs17408276 T, rs16969968 G) and CHRNA3 (rs578776 G) was associated with increased lung cancer risk (P = 0.002).
|
20587604 |
2010 |