Gene: LRRK2 ×
Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs33949390
rs33949390
LRRK2
0.020 GeneticVariation BEFREE The data suggest that LRRK1 variant (rs2924835) and LRRK2 variants (rs34594498, rs34410987, and rs33949390) are not associated with ET in this Han Chinese population. 29812962

2018
dbSNP: rs34410987
rs34410987
LRRK2
0.020 GeneticVariation BEFREE The data suggest that LRRK1 variant (rs2924835) and LRRK2 variants (rs34594498, rs34410987, and rs33949390) are not associated with ET in this Han Chinese population. 29812962

2018
dbSNP: rs33949390
rs33949390
LRRK2
0.020 GeneticVariation BEFREE Using a case control methodology, we demonstrated an association betwee</span>n a known PD risk variant, LRRK2 R1628P, with ET. 25761573

2015
dbSNP: rs34410987
rs34410987
LRRK2
0.020 GeneticVariation BEFREE To evaluate the frequency of the LRRK2 P755L variant in North American Caucasian patients with PD, we screened 426 PD patients and 37 additional patients with the combination of PD and essential tremor (ET) from our Parkinson Disease Center and Movement Clinic at Baylor College of Medicine. 17482357

2007
dbSNP: rs34594498
rs34594498
LRRK2
0.010 GeneticVariation BEFREE The data suggest that LRRK1 variant (rs2924835) and LRRK2 variants (rs34594498, rs34410987, and rs33949390) are not associated with ET in this Han Chinese population. 29812962

2018
dbSNP: rs7133914
rs7133914
LRRK2
0.010 GeneticVariation BEFREE In a case-control study involving 3198 subjects (2680 controls and 518 ET cases), R1398H was detected in 16.6% of ET cases compared to 18.0% in controls (OR = 0.91, 95% CI = 0.71-1.17, p = 0.46); while N551K was detected in 16.5% of ET cases compared to 18.0% of controls (OR = 0.89, 95% CI = 0.69-1.15, p = 0.37). 29593234

2018
dbSNP: rs7308720
rs7308720
LRRK2
0.010 GeneticVariation BEFREE In a case-control study involving 3198 subjects (2680 controls and 518 ET cases), R1398H was detected in 16.6% of ET cases compared to 18.0% in controls (OR = 0.91, 95% CI = 0.71-1.17, p = 0.46); while N551K was detected in 16.5% of ET cases compared to 18.0% of controls (OR = 0.89, 95% CI = 0.69-1.15, p = 0.37). 29593234

2018
dbSNP: rs34778348
rs34778348
LRRK2 ; LOC105369736
0.010 GeneticVariation BEFREE The LRRK2 Gly2385Arg variant is not a significant risk factor for ET in our population. 18316234

2008
dbSNP: rs34637584
rs34637584
LRRK2
0.010 GeneticVariation BEFREE Since phenotypes of PD overlap with essential tremor (ET), we investigated LRRK2 G2019S, I2012T, and I2020T mutations in a cohort of 272 patients with ET. 16939701

2006
dbSNP: rs35870237
rs35870237
LRRK2
0.010 GeneticVariation BEFREE Since phenotypes of PD overlap with essential tremor (ET), we investigated LRRK2 G2019S, I2012T, and I202</span>0T mutations in a cohort of 272 patients with ET. 16939701

2006