|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
|
31771052 |
2020 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Carriage of BDNF Val66Met has been associated with faster cognitive decline and greater hippocampal atrophy in cognitively normal elderly.
|
31771052 |
2020 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our analyses suggested the G196A (Val66Met) polymorphism was significantly associated with cog</span>nitive impairment in PD, especially in Caucasian populations.
|
31365694 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Functional rs6265 polymorphism in the brain-derived neurotrophic factor gene confers protection against neurocognitive dysfunction in posttraumatic stress disorder among Chinese patients with hepatocellular carcinoma.
|
30659644 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis implicates Val66Met BDNF polymorphism may be associated with Parkinson's disease cognitive impairment, further well-designed studies with larger populations are required to validate these results owing to the limited research.
|
31104169 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
|
30775992 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between higher BDNF levels and cognitive impairment, mainly attention in smokers appears to be dependent on the BDNF Val66Met polymorphism.
|
30659208 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined whether BDNF Val66Met variation was associated with cognitive impairment in mTLE.
|
29952080 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
While the BDNF polymorphism (rs6265) is associated with faster cognitive decline and increased hippocampal atrophy, a replicable genetic association of BDNF with AD risk has yet to be demonstrated.
|
30909233 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy.
|
30382534 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
The association between higher BDNF levels and cognitive impairment, mainly attention in smokers appears to be dependent on the BDNF Val66Met polymorphism.
|
30659208 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
A total of 1,081 adults without dementia (375 healthy subjects and 706 individuals with mild cognitive impairment) were recruited from the Alzheimer's Disease Neuroimaging Initiative (ADNI) to test the influence of BDNF Val66Met polymorphism on cognitive impairment, brain structure atrophy, and change in the levels of CSF biomarkers.
|
30775992 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Replication and Meta-analysis of the Association between BDNF Val66Met Polymorphism and Cognitive Impairment in Patients Receiving Chemotherapy.
|
30382534 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our meta-analysis implicates Val66Met BDNF polymorphism may be associated with Parkinson's disease cognitive impairment, further well-designed studies with larger populations are required to validate these results owing to the limited research.
|
31104169 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
We examined whether BDNF Val66Met variation was associated with cognitive impairment in mTLE.
|
29952080 |
2019 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our analyses suggested the G196A (Val66Met) polymorphism was significantly associated with cog</span>nitive impairment in PD, especially in Caucasian populations.
|
31365694 |
2019 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
|
29423073 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several heritability studies have reported that the Brain Derived Neurotrophic Factor (<i>BDNF</i>) Val66Met genetic polymorphism could contribute to the acceleration of cognitive decline in aging.
|
30333719 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
<i>BDNF</i> gene Val66Met variation may be associated with cognitive deficits in T2DM, especially with delayed memory.
|
29423073 |
2018 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Several heritability studies have reported that the Brain Derived Neurotrophic Factor (<i>BDNF</i>) Val66Met genetic polymorphism could contribute to the acceleration of cognitive decline in aging.
|
30333719 |
2018 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results support the hypothesis of the BDNF Val66Met polymorphism as a risk factor associated with cognitive impairment, corroborating previous findings in young and older adults.
|
28099630 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that the <i>BDNF</i> Val66Met polymorphism may play an important role in cognitive decline and could be considered as a target for novel AD therapeutics.
|
28468845 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results support the hypothesis of the BDNF Val66Met polymorphism as a risk factor associated with cognitive impairment, corroborating previous findings in young and older adults.
|
28099630 |
2017 |
|
rs759834365
|
|
|
0.100 |
GeneticVariation |
BEFREE |
These results suggest that the <i>BDNF</i> Val66Met polymorphism may play an important role in cognitive decline and could be considered as a target for novel AD therapeutics.
|
28468845 |
2017 |
|
rs6265
|
|
|
0.100 |
GeneticVariation |
BEFREE |
Our results do not support that the common genetic risk variants in rs6265 and rs1006737 are associated with cognitive dysfunction.
|
27221213 |
2016 |